Respiratory Flashcards

1
Q

COPD spirometry?

A

<0.7 and persistent

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2
Q

Goals of therapy for COPD?

A

improve exercise and IDLs and lower symptoms and exacerbations

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3
Q

Explain GOLD classifications?

A

1: FEV1 >0.8
2: FEV1 0.5-0.8
3: FEV1 0.3-0.5
4: <0.3

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4
Q

What is MRC scale?

A

1: only breathless with strenuous
2: SOB up hill
3: walk slower and have to stop
4: stop after 100 m
5: cant leave house

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5
Q

Which is better LABA or LAMA?

A

LAMA lowers exacerbations more

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6
Q

Issues with ICS in COPD?

A

increases pneumonia risk

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7
Q

Is triple therapy more efficacious than double?

A

DUH

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8
Q

Patient comes in has 1 moderate exacerbation (no hospital) and only gets breathless going up hills what therapy?

A

only bronchodilator or SABA/SAMA

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9
Q

Patient comes in has 1 severe exacerbation (hospital) and gets breathless after 100 m what therapy?

A

LABA+LAMA maybe ICS

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10
Q

Patient comes in has 1 moderate exacerbation (no hospital) and gets breathless after 100m what therapy?

A

LABA+LAMA

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11
Q

Patient comes in has 1 moderate exacerbation (hospital) and only gets breathless going up hills what therapy?

A

LABA+LAMA maybe ICS

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12
Q

When do we add ICS to therapy?

A

if eosinophils >300, or exacerbation or at risk of exacerbation, or co asthma

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13
Q

S/e of ABA?

A

high HR, BP, jittery

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14
Q

S/e of AMA?

A

dry mouth, constipation

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15
Q

What inhaler if weak lungs and weak hands?

A

genuair

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16
Q

What inhaler if strong lungs and weak hands?

A

turbuhaler, diskus, ellipta, genuair

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17
Q

What inhaler if weak lungs and strong hands?

A

breezhaler, Handihaler, genuair, MDI, Respimat

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18
Q

What inhaler if strong lungs and strong hands?

A

any inhaler

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19
Q

How to get EDS for dual or triple therapy?

A

failure of mono and then failure of double

20
Q

Comorbid conditions in COPD?

A

HF, GERD, osteoporosis, depression

21
Q

What meds should we avoid in COPD?

A

non selective BB, benzo, anticholinergics

22
Q

What is a COPD exacerbation?

A

worsening >48 hours

23
Q

What alteration of treatment in COPD exacerbations?

A

schedule SABA
O2
prednisone 30-50 mg daily

24
Q

What individuals are high risk of antibiotic failure in AECOPD?

A

FEV1 <50%, CAD, chronic oral CS use, >4 exacerbations/year, home O2, antibiotics last 3 months

25
WHat antibiotics do you give id high risk?
Amoxiclav, levofloxacin, moxifloxacin
26
Common meds that cause GERD?
caffeine/alcohol NSAID CS Bisphosphonates K Fe opioids anticholinergic CCB
27
What is VBAD for and what is it?
alarm symptoms of GERD if >50 Vomit Bleeding Abdominal mass or loss dysphagia
28
What is chart for Gi risk of NSAIDs?
High= previous COMPLICATED ulcer, >2 factors Mod (1-2 risks)= NSAID with high dose or multiple, previous ulcer, >60, ASA, CS, SSRI, CVD
29
Treatment of GERD in elderly?
prn antacid H2RA PPI
30
What is wrong with aluminum or magnesium ant acids?
DONT USE IN OLDER due to bones and toxicity
31
How long is PPI?
4-8 weeks
32
Who should be on PPI lifelong?
barretts esophagus, grade 4 erosive esophagitis, previous Gi bleed
33
S/e of PPI?
infection (cdiff), osteoporosis, nutritional deficiency
34
What are alarm features of constipation?
>50 rectal bleeding fever weight loss nocturnal abnormal labs family history of cancer or other gi diseases adominal maass
35
Medications that cause constipation?
anticholinergic opioids iron calcium CCB (verapamil the worst)
36
Lifestyle modifications to help constipation?
exercise fluids fibre
37
What form of fibre is better tolerated?
Soluble = psyllium
38
Onset of osmotic agents and examples?
1-3 days 15 min if suppository PEG, lactulose, glycerin
39
How does psyllium work and why is it bad in older people?
forms a gel with WATER= needs 250 ml of water can contribute to constipation
40
How does docusate work? is it useful?
wets and facilitates passage not great but well tolerated
41
When are saline laxatives used?
acute bowel evac is needed due to onset fast and lowers electrolytes
42
How does senna and bisacodyl work?
stimulant
43
Onset of senna?
6-12 hours
44
Which is stronger senna or bisacodyl?
bisacodyl
45
Weird s/e of senna?
urine discoloration