Respiratory Flashcards
What does a larger larynx correlate with?
Deeper Voice
The Larynx is at what level?
C4-6 in most people
Most superior region of the larynx?
Epiglottis
The epiglottis is attached to what?
Hyoid bone
Inferior portion of the pharynx
what are the functions of the larynx?
Phonation
Respiration
Name the cartilages of the larynx?
Epiglottis (1)
Cricoid (1)
Thyroid membrane (1)
Arytenoids (2)
Cornicate (2)
Cuneiform (2)
What does the thyroid membrane attach to
Superior Horns – attach to the hyoid bone by the lateral thyroid ligamament
Inferior horns – attach to the cricoid ligament through the cricothyroid ligament
What do the arytenoids do?
Abduct and Adduct the vocal cords
What muscle forms the bulk of the vocal folds?
Vocalis
What do the lateral cricoarytenoids do?
Adduct the vocal cords (close)
What do the posterior cricoarytenoids do?
Abduct the vocal cords (open)
What does the cricothyroid do?
Tenses the vocal cords (creates pitch)
What does the thyroarytenoid do?
Relaxes the vocal cords
What is the motor innervation of the larynx?
Vagus nerve
Cricothyroid = External superior laryngeal branch
Everything else = Recurrent laryngeal branch
What is the sensory innervation of the larynx above the vocal cords?
Internal Superior Laryngeal Nerve
What is the sensory innervation of the larynx below the vocal cords
Recurrent Laryngeal NerveW
What are the s/sx of injury to one side of the superior laryngeal nerve?
Hoarseness
What happens I future is damage to one side of the superior laryngeal nerve?
Voice will be affected because the vocal cord cannot stretched/tensed
can also affect gag reflex
What happens if there is damage to bilateral sides of the recurrent laryngeal nerves/
Respiratory compromise
What nerve innervates the motor to the pharynx?
Spinal accessory
What nerve innervates the pharynx to the sensory
glossopharyngeal
What is the normal P50 on the oxyhemoglobin dissociation curve?
26-27 mmHg
When the oxyhemoglobin dissociation curve shifts to the left, what happens?
Decreased PaCO2
Decreased H+ ions
increased pH
Decreased Temperature
Decreased 2,3, DPG
What happens when the oxyhemoglobin curve shifts to the left?
Left shift increases the affinity of oxygen – locked on
Left = lungs
What causes the oxyhemoglobin dissociation curve to shift to the right?
Increased PaCO2
What happens when the oxyhemoglobin curve shifts to the right?
Readily releases to the tissues from the blood
What affects the oxyhemoglobin curve?
Bohr effect
Haldane effect
Hamburger effect
How do the Haldane and Bohr effects affect the oxyhemoglobin curve?
Bohr effect helps the metabolizing tissues release oxygen from oxyhemoglobin (O2 dissociation curve)
Haldane effect helps the lungs release carbon dioxide from carboxyhemoglobin (CO2 dissociation curve)
If your SaO2 is 90, what is your PaO2
60 mmHg
If your SaO2 is 70%, what is your PaO2?
40 mmHg
What is the dissolved O2 equation?
0.003 x PaO2
O2 bound to Hbg equation
(1.34 x Hbg) (SaO2)
What is the average total oxygen consumption per minute?
3-4 ml/kg/min OR around 250 ml/min
What is the equation for dissolved CO2
0.067xPaCo2
How much (on average) Co2 is produced and eliminated per minute?
200 ml/min
Where are the primary respiratory centers located?
In the medulla
What are the primary respiratory centers?
Dorsal respiratory centers
Ventral respiratory centers
What do the dorsal respiratory centers control?
Phrenic and External intercostals
What does the ventral respiratory center control?
Internal Intercostal
What do the central chemoreceptors in the medulla respond to?
Increase H+
Increased PaCO2 in CSF
Decreased O2 <60 mmHg
Increased PaCo2
Increased H+ ions
Where are the perpipheral chemoreceptors located?
Cartoid – Glossopharyngeal nerve
Aortic – Vagus nerve (afferent)
Stretch receptors – vagus nerve
Where are the primary respiratory centers located?
in the pons
What are the secondary respiratory centers?
Apneustic Center
Pneumotaxic center
What is the apenustic center in control of?
Deep and prolonged respiration
What is the Pneumotaxic center in charge of?
Shutting off respiration
What Principe is the partial pressure of Co2 in CSF based on?
LeChatelier’s Principle
a change in one variable that describes a system at equilibrium, produces a shift in the position of the equilibrium that counteracts the effect of this change
What is an example of Lechatiler’s principle in anesthesia?
An increase in temperature will result in an increase in vapor pressure
Do pediatric patients have increased or decreased Pulmonary lung compliance? Chest wall compliance?
Decreased pulmonary lung compliance due to number of alveoli
Increased chest wall compliance
Do geriatrics have increased or decreased pulmonary lung compliance? Chest wall compliance?
Increased pulmonary lung compliance
Decreased chest wall compliance
What is the normal V/Q Matching?
4/5 = 80%
MV/CO
If your V/Q is 10/0, what does this mean?
Infinity
indicates dead space
complete ventilation, but no perfusion
Well ventilated, no perfusion
If your V/Q is 0/10, what does this mean?
0
Shunt
No ventilation, complete perfusion
Well Perfused, no ventilation
What is physiologic deadspace?
Anatomic headspace and alveolar headspace
What is anatomic Dead space?
conducting air passages + ETT
What is alveolar deadspace?
ventilation without perfusion
What increases deadspace?
Age
PP Vent
PE
Lugn disease