Respiratory

Question 1

Which opioid can also be used as an antitussive drug?

Answer 1

Butorphanol

Question 2

Adverse effects of Butorphanol when used as a cough suppressant?

Answer 2

Respiratory suppression

Question 3

Use for Trimeprazine + Prednisolone

Answer 3

(Temaril-P) anti-tussive and anti-pruritic

Question 4

Mechanism of action of Albuterol

Answer 4

Acts as an agonist on β2 adrenergic receptors

Question 5

Indicated effect of albuterol

Answer 5

Bronchodilator

Question 6

Adverse effects of albuterol

Answer 6

Adrenergic effects

Question 7

Mechanism of action of terbutaline

Answer 7

Agonist at β2 receptors

Question 8

Adverse effects of terbutaline

Answer 8

Adrenergic effects

Question 9

Mechanism of action of clenbuterol

Answer 9

Agonist activity at β1 more than β2

Question 10

Contraindications of clenbuterol

Answer 10

Explicitly forbidden for use in cattle!

Question 11

Why is epinephrine not commonly used for it’s respiratory effects?

Answer 11

Epi is non-specific, which means it will bind to adrenergic receptors throughout the body, not just in the lungs. So the patient will have an increase in adverse adrenergic effects

Question 12

Theophylline mechanism of action

Answer 12

Inhibits phosphodiesterase in smooth muscle cells from causing bronchoconstriction

Question 13

Contraindications of theophylline use

Answer 13

It has stimulant properties and risks of drug interactions. Not approved for use in veterinary medicine, all use is extra label

Question 14

Mechanism of action of Tripelennamine

Answer 14

H1 blocker (antihistamine)

Question 15

Indicated effect of Dopram

Answer 15

Stimulates ventilation

Question 16

Mechanism of action of dopram

Answer 16

Inhibits potassium channels on carotid body chemoreceptors , therefore increases sensitivity to CO2 and stimulates respiration

Question 17

Benefits of nebulized drug administration

Answer 17

Almost immediate effects