Respiratory

Question 1

Name 2 Short acting beta 2 adrenoreceptor agonist

Answer 1

Salbutamol
Terbutaline

Question 2

Name 3 ways SABAs are administered

Answer 2

Meter dosed inhalers
Dry powder inhaler
Spacers and nebulisers

Question 3

How does SABA work?

Answer 3

Bronchodilators so dialtes the smooth muscle in the lungs

Question 4

What channels do SABA stimulate

Answer 4

N+ AND K+
Moves K+ out of the cells

Question 5

Name 5 side effects

Answer 5

1) Palpitations
2) Tachycardia
3) Hypokelemia (lowers K+ in blood)
4) Hand tremors
5) Tolerance - the more they use it, the less effective it is overtime

Question 6

Name 3 inhaled corticosteroids used in asthma

Answer 6

1) Beclomethasone
2) Budesonide
3) Fluticasone

Question 7

Name effects of ICS

Answer 7

1) reduce mucosal inflammation
2) Widens airways
3) Reduces mucus secretions

Question 8

Using fluticasone in patients with COPD can increase risk of ….?

Answer 8

Pneumonia

Question 9

What receptors do ICS bind to?

Answer 9

binds to receptors in cytoplasm and move to cell nucleus.

Question 10

How do ICS work?

Answer 10

They produce lipocortin which inhibits the cascade of prostaglandin, leukotrienes, chemokines and cytokines which leads to inflammatory response.

Question 11

What are side effects of ICS?

Answer 11

Oral candida