Respiratory Flashcards

1
Q

Causes of tracheal deviation

A
  1. Towards the side of the lung lesion
    a. Upper lobe collapse
    b. Upper lobe fibrosis
    c. Pneumonectomy
  2. Away from the side of the lung lesion (uncommon)
    a. Massive pleural effusion
    b. Tension pneumothorax
  3. Upper mediastinal masses, such as retrosternal goitre
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2
Q

Signs of consolidation

A

● Expansion: reduced on the affected side
● Vocal fremitus: increased on the affected side
● Percussion: dull but not stony dull
● Breath sounds: bronchial
● Additional sounds: medium, late or pan-inspiratory crackles as the pneumonia resolves
● Vocal resonance: increased
● Pleural rub: may be present

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3
Q

Signs of atelectasis

A

● Trachea: displaced towards the affected side
● Expansion: reduced on the affected side with flattening of the chest wall on the same side
● Percussion: dull over the collapsed area
● Breath sounds: reduced, nil added sounds

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4
Q

Signs of pleural effusion

A

● Trachea and apex beat: displaced away from a massive effusion
● Expansion: reduced on the affected side
● Percussion: stony dullness over the fluid
● Breath sounds: reduced or absent. May be an area of bronchial breathing audible above the effusion due to compression of overlying lung
● Vocal resonance: reduced

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5
Q

Causes of a pleural effusion

A

● Transudate
o Cardiac failure
o Hypoalbuminaemia from nephrotic syndrome or chronic liver disease
o Hypothyroidism
o Meigs syndrome (ovarian fibroma causing pleural effusion and ascites)
● Exudate
o Pneumonia
o Neoplasm – bronchial carcinoma, metastatic carcinoma, mesothelioma
o Tuberculosis
o Pulmonary infarction
o Subphrenic abcess
o Acute pancreatitis
o Connective tissue disease (e.g. rheumatoid arthritis, SLE)
o Drugs such as methysergide, cytotoxics
o Irradiation
o Trauma
● Haemothorax
o Severe trauma to the chest
o Rupture of a pleural adhesion containing a blood vessel
● Chylothorax
o Trauma or surgery to the thoracic duct
o Carcinoma or lymphoma involving the thoracic duct
● Empyema
o Pneumonia
o Lung abscess
o Bronchiectasis
o Tuberculosis

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6
Q

Lights criteria

A

The formal definition of an exudate is that the fluid has at least one of the following Light’s criteria:

  1. Fluid protein/serum protein >0.5
  2. Pleural fluid LDH/serum LDH >0.6
  3. Pleural fluid LDH >2/3 of normal upper limit of LDH in serum
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7
Q

Signs of a lobectomy

A

● Thoracotomy scar
● Tracheal deviation (in upper lobectomy or pneumonectomy)
● Ribs may be pulled in
● Reduced chest expansion
● Dull percussion note
● Reduced breath sounds with possible overlying bronchial breathing
● Possible displaced apex beat

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8
Q

Signs of a pneumothorax

A

● Expansion: reduced on the affected side
● Percussion: hyperresonnace if the pneumothorax is large
● Breath sounds: greatly reduced or absent
● There may be subcutaneous emphysema

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9
Q

Signs of bronchiectasis

A

● Systemic signs: fever, cachexia, sinusitis
● Clubbing and cyanosis
● Sputum: voluminous, purulent, foul-smelling sometimes blood-stained
● Course pan-inspiratory or late inspiratory crackles over the affected lobe
● Signs of severe bronchiectasis
o Very copious sputum and bronchiectasis
o Clubbing
o Widespread crackles
o Signs of airway obstruction
o Signs of respiratory failure and cor pulmonale

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10
Q

Signs of COPD

A

● Barrel-shaped chest with increased anteroposterior diameter
● Pursed-lip breathing
● Use of accessory muscles of respiration and drawing in of the lower intercostal muscles with inspiration
● Palpation: reduced expansion and a hyperinflated chest, tracheal tug
● Percussion: hyperresonant with decreased liver dullness
● Breath sounds: decreased, early inspiratory crackles
● Signs of right heart failure

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11
Q

Signs of ILD

A

● General: dyspnoea, cyanosis and clubbing
● Palpation: expansion is slightly reduced
● Auscultation: fine (Velcro-like) late inspiratory or pan-inspiratory crackles heard over the affected lobes
● Signs of associated connective tissue disease: rheumatoid arthritis, systemic lupus erythematosus, scleroderma, Sjogren’s syndrome, polymyositis and dermatomyositis

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12
Q

Causes of interstitial fibrosis

A
Upper lobe predominant (SCHART)
●	S = silicosis, sarcoidosis
●	C = coal worker’s pneumoconiosis
●	H = histiocytosis
●	A  = ankylosing spondylitis, allergic bronchopulmonary aspergillosis 
●	R = radiation
●	T = tuberculosis 
Lower lobe predominant (ARSIO)
●	A = asbestosis
●	R = rheumatoid arthritis 
●	S = scleroderma
●	I = idiopathic interstitial fibrosis
●	O = other (drugs e.g. busulfan, bleomycin, nitrofurantoin, hydralazine, methotrexate, amiodarone), other collagen vascular diseases, acute allergic alveolitis, acute eosinophilic pneumonitis
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13
Q

Difference between UIP and NSIP

A

UIP - Usual interstitial pneumonia

  • associated with IPF and RA
  • Honeycombing
  • normal lung alternating with interstitial fibrosis and honeycombing.
  • apicobasal gradient
  • sub pleural involvement
  • reticular opacities
  • traction bronchiectasis

NSIP - Nonspecific interstitial pneumonia

  • ground glass opacities
  • reticular opacities
  • traction bronchiectasis
  • subpleural sparing
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14
Q

Extra-pulmonary signs of sarcoidosis

A

● Skin: lupus pernio (violaceous patches on the face), pink nodules and plaques in old scars, erythema nodosum on the shins
● Eyes: ciliary injection, anterior uveitis
● Lymph nodes: generalised lymphadenopathy
● Liver and spleen: enlarged (uncommon)
● Parotids: gland enlargement (uncommon)
● Central nervous system: cranial nerve lesions, peripheral neuropathy (uncommon)
● Musculoskeletal system: arthralgia, swollen fingers, bone cysts (rare)
● Heart: heart block presenting as syncope, cor pulmonale (rare)
● Signs of hypercalcaemia

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15
Q

Causes of bronchial breath sounds

A
  • lobar pneumonia
  • localised fibrosis or collapse
  • above a pleural effusion
  • large lung cavity
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16
Q

Causes of reduced breath sounds

A
  • emphysema
  • large lung mass
  • collapse, fibrosis, or pneumonia
  • effusion
  • pneumothorax
17
Q

Causes of wheeze

A

inspiratory: asthma; upper airway extrathoracic obstruction
expiratory: asthma; COPD
fixed inspiratory (monophonic = no change with respiration): fixed bronchial obstruction (think carcinoma)

18
Q

Causes of crackles

A
late/pan inspiratory 
fine: fibrosis 
medium: LVF 
coarse: bronchiectasis or retained secretions 
early inspiratory 
coarse: COPD
19
Q

Investigations in bronchiectasis

A

CXR - cystic changes
HRCT - tram tracking
Sputum - MCS - infection
Spirometry - obstructive lung disease. No reversibility.
Immunoglobulins - hypogammaglobulinemia
CFTR transporter gene
IgE level + allergic skin testing - ABPA
Ciliary beat testing for ciliary dysfunction

20
Q

Complications of Bronchiectasis

A
Cor Pulmonale 
Massive Haemoptysis 
Recurrent pneumonias/ sepsis 
Pulmonary hypertension 
Pneumothorax
21
Q

Causes of Bronchiectasis

A

Congenital

  • hypogammaglobulinemia
  • Cystic fibrosis
  • immotile cilia syndrome
  • Young syndrome

Acquired

  • recurrent childhood respiratory infections - measles, pertussis, bronchiolitis, TB.
  • Auto-immune - RA, IBD.
  • ABPA
  • Obstructing lesions
  • ILD