respiration Flashcards
importance of respiration for organisms
all organisms need to carry out respiration in order to make energy available in cells
what is respiration (include example)
Respiration is a catabolic process involving a series of enzyme-catalysed reactions in cells.
Energy-rich respiratory substrates, such as glucose and fatty acids, are broken down to release energy.
what happens to the energy
Some of the energy is transferred to chemical energy in ATP (adenosine triphosphate) and some is released as heat energy.
what happens during respiration? (bonds, energy)
During respiration, high energy C-C, C-H and C-OH bonds are broken, lower energy bonds are formed, and the
remaining energy is released and used to attach inorganic phosphate to ADP (adenosine diphosphate) to make ATP.
types of respiration
aerobic respiration
anaerobic respiration
what is aerobic respiration
Aerobic respiration is when a glucose molecule is completely broken down to carbon dioxide and water in a series of reactions.
stages in aerobic respiration
glycolysis
link reaction
Krebs cycle
electron transport chain
where does glycolysis take place
in the cytosol
does not require o2
3 stages of glycolysis
- The phosphorylation of glucose. The hydrolysis of 2 ATP molecules provides the phosphate. The 6C hexose bisphosphate that is formed is unstable with a low activation energy.
- The splitting of the 6C hexose bisphosphate formed into two 3C triose phosphate molecules.
- The oxidation of each of triose phosphate to 3C pyruvate through the loss of hydrogen – this is through the action of a dehydrogenase enzyme. ATP is produced by substrate level phosphorylation in this process (2 ATP per triose phosphate).
what does glycolysis produce?
-a net yield of 2 ATP produced by substrate level phosphorylation
-2 molecules of reduced NAD (also written as NADH2 and NADH + H+)
-2 pyruvates.
[NAD = nicotinamide adenine dinucleotide]
where does link reaction take place?
matrix of mitochondria
o2 involvement and link reaction
If oxygen is available, the pyruvate produced in the cytosol is actively transported into the matrix of the mitochondria.
what does link reaction do
links glycolysis and Krebs cycle
what does link reaction involve/ steps
3C pyruvate molecules are converted to 2C acetate (C2H5-) through the loss of a carbon dioxide (in modern Chemistry acetate is called ethyl but we still use acetate in this context)
carbon dioxide is produced through the action of a decarboxylase enzyme
hydrogen is lost through the action of a dehydrogenase enzyme
NAD is reduced by the hydrogen to NADH2
acetate is activated by combining with co-enzyme A to produce acetyl co-enzyme A.
What enters the Krebs cycle and where does it take place?
Each acetyl co-enzyme A enters the Krebs cycle, which takes place in the matrix of mitochondria.