Respiration Flashcards
Glycolosis
Glucose is phosphorylated to glucose phosphate using ATP.
This is unstable so split into 2 TP. Oxidised by NAD and produces 2ATP for each TP, producing pyruvate.
Where does glycolosis occur?
Cytoplasm
Link reaction
Pyruvate actively transported from the cytoplasm to the mitochondrial matrix.
NAD oxidises pyruvate into acetate and decarboxylates it.
Acetate combines with coenzyme A to produce acetyl coenzyme A.
Krebs cycle
acetyl coenzyme A combines with a 4C molecule (oxaloacetate) to produce a 6C molecule. The 6C molecule is decarboxylated and oxidised with NAD to produce a 5C molecule. CO2 and NADH produced.
5C molecule further decarboxylated and oxidised by NAD to a 4C molecule, producing CO2 and NADH again. The 4C molecule is further oxidised by NAD and FAD to produce another 4C molecule oxaloacetate. This provides energy for the reaction of ADP +Pi goes to ATP.
What are the NADH and FADH formed from the krebs cycle used for?
e- and H+ donors in oxidative phosphorylation.
Products from the Krebs cycle and link reaction
8x NADH
2x FADH
2x ATP
6x CO2
Products from Krebs cycle per glucose molecule
6x NADH
2x FADH
2x ATP
4x CO2
Products from link reaction per glucose molecule
2x NADH
2x acetyl coenzyme A
2x CO2
Products of glycolisis
2x pyruvate
net gain of 2 ATP
2x NADH
What is phosphorylation
making something more reactive by adding a phosphate