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Cardioresp > Resp Pharma > Flashcards

Resp Pharma Flashcards

1
Q

Examples of short acting beta agonists

A

Salbutamol

Terbutaline

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2
Q

Long acting beta agonists

A

Formeterol

Salmeterol

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3
Q

Action of beta agonists

A

Increase cAMP in smooth muscle cells

Leading to dilation

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4
Q

Beta agonists metabolism and excretion

A

Liver

Urine

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5
Q

Beta agonists side effects

A 
Tremor
Headache
Palpitations 
Tachycardia
GI upset 
Hypokalaemia
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6
Q

Example short acting antimuscarinic

A

Ipratropium

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7
Q

Example long acting muscarinic

A

Tiotropium

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8
Q

Mechanism of antimuscarinics

A

Decrease cGMP

Causes decreased SMC contractility

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9
Q

Metabolism and excretion of antimuscarinics

A

Partially metabolised in liver

Excreted in urine

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10
Q

Examples of xanthines

A

Aminophylline

Theophylline

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11
Q

Mechanisms of xanthines

A

Block phosphodiesterase
less cAMP breakdown
Bronchodilation

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12
Q

Metabolism and excretion of xanthines

A

Liver

Urine

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13
Q

Side effects of xanthines

A 
Headache
GI upset
Reflux
Palpitations
Dizziness
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14
Q

Inhaled glucocorticoids examples

A

Beclomethosone
Budesonide
Fluticasone

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15
Q

Action of glucocorticoids

A

Decrease bronchial inflammation

Modify allergic reactions

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16
Q

Metabolism and excretion of glucocorticoids

A

Liver

Urine

17
Q

Side effects of glucocorticoids

A

Cough
Thrush
Taste changes
Hoarseness

18
Q

Oral/IV glucocorticoids

A

Prednisolone
Hydrocortisone
Dexamethosone
Triamcinolone

19
Q

Mechanism of non inhaled glucocorticoids

A

Altered gene transcription

20
Q

Metabolism and excretion of glucocorticoids

A

Liver

Urine

21
Q

Side effects of glucocorticoids

A 
Adrenal suppression 
Hyperglycaemia 
Psychosis
Insomnia
Indigestion 
Mood swings

Cardioresp (6 decks)

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