Resp/Cardio/GI/

Question 1

Native valve endocarditis (sub-acute)

Answer 1

Amoxicillin IV 2g 4 hourly + Gentamicin 1mg/kg (NAG)

Question 2

Native valve endocarditis (acute sepsis) or IVDU

Answer 2

Flucloxicillin IV 2g 6 hourly

Question 3

Prosthetic valve endocarditis or MRSA

Answer 3

Vancomycin IV + Rifampicin PO 600mg + Gentamicin IV 1mg/kg (VGR-ous treatment)

Question 4

Non-severe C. Difficile

Answer 4

Metronidazole PO 400mg

Question 5

Severe C. Difficile

Answer 5

Vancomycin 125mg qd PO (only time you give it orally) +/- IV Metronidazole

Question 6

Peritonitis/Biliary tract/Intra-abdominal

Answer 6

IV Amoxicillin + Metronidazole + Gentamicin
(then step down to PO Co-trimoxazole + Metronidazole)
If penicillin allergic: IV Vancomycin + Metronidazole + Gentamicin

Question 7

Gastroenteritis

Answer 7

No antibiotic treatment required unless systemic

Question 8

Systemic campylobacter

Answer 8

Erythromycin or Ciprafloxin for 5 days

Question 9

Systemic salmonella

Answer 9

Ciprafloxin for 5 days

Question 10

Typhoid/paratyphoid fever

Answer 10

Depending on sensitivities. IV Ceftriaxone if unstable

Question 11

Any unknown infection

Answer 11

IV Amoxicillin + Metronidazole + Gentamicin

if allergic IV Vancomycin + Metronidazole + Gentamicin

Question 12

Giardia

Answer 12

Oral Metronidazole

Question 13

Threadworms

Answer 13

Oral Mebendazole

Question 14

4 C’s antibiotics associated with C. Difficile

Answer 14

Clindomycin, Cephalosporin, Co-amoxiclav, Ciprafloxin

Question 15

Amoebiasis

Answer 15

Metronidazole and remove from lumen with diloxinide furate or puromycin

Question 16

Prophylaxis for travellers diarrhoea

Answer 16

Ciprafloxicin

Question 17

Mild/moderate CAP

Answer 17

Amoxicillin 1g IV/PO

if allergic: Doxycycline 200mg on Day 1 then 100mg

Question 18

Severe CAP

Answer 18

Co-amoxiclav IV + Clarithromycin IV or Doxycycline PO

If allergic: IV levofloxacin

Question 19

Severe Hospital Acquired Pneumonia

Answer 19

IV Amoxicillin + Metronidazole + Gentamicin

if penicillin allergic: IV Co-trimoxazole + Metronidazole +/- Gentamicin

Question 20

Non-Severe Hospital Acquired Pneumonia

Answer 20

PO Amoxicillin 1g + Metronidazole 400mg

if penicillin allergic: PO Co-trimoxazole + Metronidazole

Question 21

COPD (if purulent sputum) or LRTI

Answer 21

1st line: Amoxicillin 500mg

2nd line: Doxycycline 200mg then 100mg

Question 22

CRB 65 Score

Answer 22

Confusion new MSQ >8/10
RR >30/min
BP 65 years

Question 23

0-1 CRB 65 score

Answer 23

Usually treat at home

Question 24

2 CRB 65 score

Answer 24

Consider hospital referral

Question 25

3-4 CRB 65 score

Answer 25

Urgent hospital admission

Question 26

Diverticulitis (only if antibiotics indicated)

Answer 26

Metronidazole 400mg + Co-trimoxazole 960mg