Resp 10 - Lung infections: viral and bacterial pneumonias

Question 1

What are the two pneumonia causes?

Answer 1

• Nosocomial

- Community acquired (CAP)

Question 2

What are CAP causes?

Answer 2

62% ‘no pathogen detected’

1. strep pneumoniae - typical
2. mycoplasma pneumoniae - atypical
3. Staph. Aureus

Question 3

What are Hospital acquired pneumonia causes?

Answer 3

• Staph aureus (28%)
• Pseudomonas aeruginosa (21.8%)
• Klebsiella species (9.8%)
• E.Coli (6.9%)

Question 4

What causes severe disease?

Answer 4

RNA sequence, viral load
Host - Environment, DNA
Epithelial damage + bacteria
Mediators - cell stress

Basically:
Highly pathogenic strain
Absence of prior immunity
Weakened host immune response

Question 5

To what disease does an RSV infection predispose you to?

Answer 5

Asthma