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Antimicrobials > Resistance Testing > Flashcards

Resistance Testing Flashcards

1
Q

What test is performed for inducible clindamycin resistance?

A

D-Test

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2
Q

What organisms can be tested for inducible clindamycin resistance?

A

Staphylococcus species (inc S. aureus and S. lugdunensis, and CoNS)
Streptococcus pneumoniae
B-hemolytic Streptococcus species

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3
Q

What criteria should an organism have to be tested for inducible clindamycin resistance?

A

R to erythromycin and S or I to clindamycin

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4
Q

What gene confers macrolide resistance? How does it confer resistance?

A 
Erm gene (methyl transferase)
Methylates an Adenine in the 23s rRNA macrolide binding site (of the 50s ribosomal subunit)
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Antimicrobials (3 decks)

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