Resistance Mechanisms

Question 1

Name drug whose effectiveness is reduced by

Altered Penicillin Binding Proteins

Answer 1

Penicillins

Question 2

Name drug whose effectiveness is reduced by

Acid

Answer 2

Penicillin G
Methicillin
Amoxicillin
Aminoglycosides
- Streptomycin
- Gentamycin

Question 3

Name drug whose effectiveness is reduced by

altered membrane permeability to the drug

Answer 3

Cephalosporins

Question 4

Name drug whose effectiveness is reduced by

An alternative protein that is encoded on a plasmid

Answer 4

Trimethoprim

Question 5

Name drug whose effectiveness is reduced by

altered cell well precusors

Answer 5

Vancomycin

Question 6

Name drug whose effectiveness is reduced by

bacterial efflux pumps

Answer 6

Tetracyclines

Question 7

Name drug whose effectiveness is reduced by

methylation of 23S ribosomal RNA

Answer 7

Erythromycin

Question 8

Name drug whose effectiveness is reduced by

Detoxification by acetylation of the hydroxyl group

Answer 8

Chloramphenicol