Research presentation on drug abuse and cognitive decline Flashcards
1
Q
Drugs affecting the brain
A
Impaired cognition = AAS, opioids, central stimulants, y-hydroxybutyrate (GHB), tetrahydrocannabinol (THC)
2
Q
AAS effects cognitive function in rats
A
AAS causes reduction in the number of neurons in hippocampus, parietal cortex + prefrontal cortex regions + increases oxidative damage
3
Q
Opiates+ cognition
A
Long term use of opiates may lead to negative effects on learning + memory
4
Q
Growth hormone in learning + memory fuction
A
GH replacement therapy produces improved short term + long term memory
GH affects cognitive functions in rats
GH improves cognitive capabilities in hypophysis-ectomised rats- NMDA subunits upregulated