Research presentation on drug abuse and cognitive decline Flashcards

1
Q

Drugs affecting the brain

A

Impaired cognition = AAS, opioids, central stimulants, y-hydroxybutyrate (GHB), tetrahydrocannabinol (THC)

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2
Q

AAS effects cognitive function in rats

A

AAS causes reduction in the number of neurons in hippocampus, parietal cortex + prefrontal cortex regions + increases oxidative damage

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3
Q

Opiates+ cognition

A

Long term use of opiates may lead to negative effects on learning + memory

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4
Q

Growth hormone in learning + memory fuction

A

GH replacement therapy produces improved short term + long term memory
GH affects cognitive functions in rats
GH improves cognitive capabilities in hypophysis-ectomised rats- NMDA subunits upregulated

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