Research Ethics Flashcards
1
Q
What are the 3 principles of research ethics?
A
- Respect for persons: respect for autonomy, informed consent
- Beneficence: maximizing benefits, minimizing risks
- Justice: fair distribution of costs and benefits of research
2
Q
When does ethics matter in research?
A
- Designing a study
- Recruiting/enrolling patients (discussing or recommending participation to individual patients as a treating physician)
- Monitoring the study (stopping rules)
- Publishing/disseminating results (publication bias)
- Reading a study (changing your practice based on study conclusions)
3
Q
What is the Nuremberg code?
A
A set of principles with regard to ethical research on human subjects, developed in response to Nazi scientist crimes against humanity.
- Voluntary and informed consent from competent subject
- Results should be positive and not able to be obtained without human subjects
- Based on existing scientific knowledge
- Minimize/avoid unnecessary suffering
- No risk of death or permanent disability
- Risks in proportion to humanitarian benefits
- Protect subjects from risks
- Staff must be qualified
- Subjects can quit at any time
- Must stop study if it becomes apparent that the risks are too great
