Required drugs Flashcards
1
Q
NSAIDS
A
adequate for mild pain and fever (COX-1) and suppression of inflammation (COX-2) at high doses
2
Q
Aspirin (ASA)
A
NSAID prototype
(Oral, 325 mg tablets)
(650-100 mg) [3-4 tablets] / 4 hours
- headache, arthritis, dysmenorrhea, neuralgia, myalgia,
(>1300 mg) [4+ tablets] /4 hours
- acute rheumatic fever, RA, etc.
( 75-81 mg/day) (1/4 of normal dose)
Prevents thrombus formation
– prevent risk of stroke, MI, and transient ischemia (TIA)
(-) increased bleeding, , GI irritation and damage, mild GI bleeding, peptic ulcers, gastric ulceration, and hemorrhage
(+) reduces GI cancer risk
Do not take with warfarin, methotrexate, sulfasinomides, etc.
3
Q
Celocoxib
A
Prototype COX-2 inhibitor
Used to treat inflammation and sometimes pain with fewer unwanted COX-1 effects
