REPRODUCTIVE SYSTEM PHYSIOLOGY COPY Flashcards
What is the age of a neonate?
First month after birth
What is the age of an infant?
First year after birth
Details of the organs of the fetus are established when?
2nd-3rd month
When the organs of the fetus will be the same as that of neonate?
4th month
When cellular development takes place in fetal development?
5th month
Fetal development starts when?
First month
The heart begins to beat at fourth week after fertilization. What is the HR?
65 beats/min
At 3rd month onwards of fetal development, what will be the principal source of RBC and most of the WBC?
Bone marrow
At 6th week of fetal development, what will begin to form blood cells?
Liver
At 3rd month of fetal development, what organs will begin to form blood cells?
Spleen and other lymphoid tissues of the body
What system cannot occur during fetal life, it is inhibited to prevent fluid and debris to fill in?
Respiratory system. There is no air to breathe in the amniotic fluid. Inhibition of this system prevents filling of fluid and debris (meconium) into the lungs.
Stool of fetus excreted into amniotic fluid?
Meconium. It is a residue form swallowed amniotic fluid and mucus, epithelial cells and other residues of excretory products from the GI mucosa and glands.
Impairment of this organ leads to oligohydramnios?
During 4-6 months of pregnancy, fetal kidneys begin to excrete fetal urine which is 70-80% of amniotic fluid. Impairment of fetal kidneys lead to reduced fetal urine > reduced amniotic fluid > oligohydramnios
Reflexes of fetus are present when?
3rd to 4th month
It is a switch from intrauterine to extrauterine. It requires higher metabolic needs (anabolism. It is a period of rapid growth and development. The systems are immature at this period.
Neonatal physiology
Normally, how many minutes will the neonate start to breathe?
a. ) Within one hour
b. ) Within 30 seconds
c. ) Within one minute
d. ) Within one second
C.) Within one minute. Loss of placental support so respiratory system starts to function. Neonate starts to breathe. Begins to breathe within seconds. Normal RR within 1 min after birth. Breathing is initiated by sudden exposure to outside world.
When the newborn progressively becomes hypoxic, hypercapnic, and acidotic, these provide stimulus to respiratory center and usually causes breathing within an additional minute after birth.
What would be the consequence to the neonate for giving excessive anesthesia to the mother during delivery?
a. ) Increased heart rate
b. ) Delayed urinary function
c. ) Meconium is increased
d. ) Delayed onset of respiratory
d.) Delayed onset of respiratory.
Other causes:
- ) Umbilical cord compression,
- ) Premature separation of the placenta
- ) Excessive contraction of the uterus
TRUE OR FALSE: The neonate can tolerate delayed breathing up to 15 minutes.
FALSE. The neonate can tolerate up to 10 minutes while adult can tolerate only 4 minutes delay of breathing. Permanent brain damage may occur after atleast 8 minutes.
Required pressure to oppose the surface tension in the collapsed alveoli of newborn?
25mmHg of negative inspiratory pressure
Bypasses the liver during fetal life?
a. ) Ductus venosus
b. ) Ductus arteriousus
c. ) Ductus ovale
a.) Ductus venosus. Within 1-3 hrs after birth muscle wall of ductus venosus constricts shutting off blood flow, and causes blood to flow to the liver.
Due to production of vasodilating
prostaglandins specifically PGE2, the closure of this duct is prevented?
Ductus arteriosus
Least role in reoxygenation during fetal life?
a. ) placenta
b. ) fetal lungs
c. ) maternal lungs
d. ) tissues of the fetus
b.) fetal lungs
- TAKE NOTE: REOXYGENATION OF FETAL BLOOD HAPPENS AT THE PLACENTA OF THE MOTHER 55% GOES TO PLACENTA 45% GOES TO TISSUES OF THE FETUS 12% GOES TO FETAL LUNGS BEFORE BIRTH
Blood glucose concentration during first day of neonate after birth?
30 to 40 mg/dl of plasma (less than half the normal value)
Things that will happen least during first few days of neonate after birth?
a. ) Physiologic weight loss
b. )Blood glucose concentration frequently falls the first day
c. ) Has no sufficient fats and protein stores during first 3 days
c.) has no sufficient fats and protein stores during first 3 days
Neonatal Nutrition:
Blood glucose concentration frequently falls the first day =
30 to 40 mg/dl of plasma (less than half the normal value)
• Has stored fats and proteins for metabolism until mother’s
milk can be provided 2 to 3 days later
• Special problems: adequate fluid supply to the neonate
because the infant’s rate of body fluid turnover averages
seven times that of an adult, and the mother’s milk supply
requires several days to develop.
• Physiologic weight loss = decrease of 5 -10 % (as much as
20%) within the first 2 to 3 days of life due to fluid loss
• After birth liver and muscle glycogen is sufficient only for a
few hours
Macrosomal babies common cause?
Macrosomal babies (large babies) born to Type II DM
mothers
▪ The high levels of insulin are believed to stimulate fetal
growth and contribute to increased birth weight
▪ Increased supply of glucose and other nutrients to the
fetus may also contribute to increased fetal growth
▪ Associated with organomegaly
▪ When blood supply is cut off, glucose levels drop, if
insulin is still high, causing hypoglycemia,
▪ Neonates can be at risk for respiratory distress syndrome
o In the mother with uncontrolled type I diabetes (caused by
lack of insulin secretion), fetal growth may be stunted
because of metabolic deficits in the mother and growth and
tissue maturation of the neonate are often impaired.
Placenta and colostrum can protect the infant for how many months?
Passive Immunity from the mother
(through the placenta and colostrum in milk)
- Can protect the infant for about 6 months against most
major childhood infectious diseases, including diphtheria,
measles, and polio
- Decrease of antibodies to less than half at age 1 month
- Gradual return of gamma globulin concentration to normal
by the age of 12 to 20 months
Start of complimentary feeding for
the neonate?
Note: 6th month is the start of complimentary feeding for
the neonate before then, it is advised that neonates be
given only breast milk
Required for proper formation of cartilage,
bone, and other intercellular structures of the infant?
Vitamin C
If the mother had anemia, severe anemia is likely to occur in the infant after about 3 months. What shall you do?
Necessity for Iron in the Diet
o May have stored enough iron to keep forming blood
cells for 4 to 6 months after birth
o If the mother had anemia, severe anemia is likely to occur
in the infant after about 3 months of life
o May feed infant with egg yolk or give iron supplement by
the second or third month of life
Humans have how many pairs of chromosomes?
Humans have 23 pairs of chromosomes
o 22 pairs of autosomes
o 1 pair of sex chromosomes
Male: XY Female: XX
gametes or sex cells contain how many sets of chromosomes?
Haploid (n) contain one complete set of chromosomes
Also called Equational Division?
Equational Division
because it brings back or restore the amount of DNA in a
cell, from double stranded DNA it ensures that it will form
a single strand of DNA only. At the end of meiosis you’ll
have four non-identical haploid daughter cells.
TRUE OR FALSE. During 6th month of pregnancy, diploid state of organism is restored and genetic sex determination occurs.
Sex Determination - process of genetic inheritance that sets the gender of an
individual at the moment of fertilization. Remember that at fertilization, there are 2 important genetic events that occur. It is when the male and female nuclei unites:
1.) Diploid state of organism is restored and
2.) Genetic sex of organism can now be identified. (Male: XY Female:XX)
development of differences between males and females
from an undifferentiated zygote?
Sex Differentiation
GnRH is produced in the
Arcuate nuclei
In hair root test, presence of fluorescent body means?
a. ) the patient is male
b. ) the patient is female
c. ) the patient is pregnant
d. ) the patient is hungry
A. The patient is male. A fluorescent body is Y chromosome.
What secretes Mullerian Inhibiting Factor (MIF)?
Sertoli cells
What secretes testosterone?
Leydig cells
Largest somatic chromosome?
Chromosome 1
Smallest somatic chromosome?
Chromosome 22
Cells in meiosis II are?
a. ) haploid
b. ) diploid
c. ) mongoloid
A.) Haploid. After meiosis II, four daughter cells (haploid) are produced.
Milk producing hormone
Prolactin
Presence or absence of SRY gene?
Gonadal sex
A XX fetus was injected with testosterone. She will be,
a. ) genetically male, phenotypically male
b. ) genetically female, phenotypically male
c. ) genitically female, phenotypically female
B.
Stage of oocyte when the sperm invites the follicle?
Secondary
Opposite of telophase?
Prophase
Which comes from wolffian duct?
a. oviduct
b. clitoris
c. scrotum
d. vas deferens
D
During pregnancy, fetal blood is ______ , maternal blood is ___________.
Alkaline, acidic
What encodes for SRY protein?
Chromosome Y
Lyon hypothesis states that
One of the 2X chromosomes in the female will be inactivated