Reproductive System - II Flashcards

1
Q

describe the accessory structure, the scrotum

A

contains:
- two testes
- two epididymides
- two spermatic cords (with part of ductus deferens)

  • houses testes away fro the body to maintain temperature at ~34 decrees celsius
  • scrotum lined by dartos muscle - lines inside of scrotum, when it contracts it wrinkles the skin, decreasing the surface area needing to be heated
  • cremaster muscle - contracts for heat conservation, covers spermatic cord and testes, brings them up closer to the body for heating
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2
Q

describe the spermatic cord

A
  • there are two spermatic cords
  • runs between abdomen and testes
  • contains: ductus deferens, blood vessels - testicular artieries and veins (veins are called venous plexus, which is like a web around the artery, increasing the surface area for thermal exchange to cool the blood from the body to the ~34 degrees), nerves, lymphatics
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3
Q

describe the accessory structure, the penis

A

dual function:
- urination
- copulation
cylindrical organ:
- root (bulb): where the penis is adhered to the urogenital triangle of the body wall
- body
- glans covered by prepuce/foreskin

contains three cylindrical erectile tissues:
Two corpora cavernosa (sing. = corpus cavernosum):
- main erectile tissue
- dorsal aspect
One corpus spongiosum:
- contains urethra
- forms bulb and glans
- ventral aspect
- not as much erectile tissue because don’t want to block urethra

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4
Q

describe the accessory glands

A
  • spermatozoa carried to female reproductive tract in seminal fluid (together called semen)
  • seminal fluid is mostly proceeds by three types of accessory glands
    - seminal vesicles
    - prostate gland
    - bulbourethral glands
  • seminal fluid functions: fluid medium to carry spermatozoa from male to female reproductive tracts, protection for the spermatozoa against acidic vagina or urine, energy/nutrition for the spermatozoa, lubrication, motility (interaction between seminal fluid and spermatozoa cause motility)
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5
Q

describe the seminal vesicles

A

two glands located:
- posterior to bladder
- lateral to ampulla
produce viscous secretion:
- makes ip ~60% of semen
- alkaline pH protects sperm against acidic environment in urethra and vagina

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6
Q

describe the prostate gland

A

location:
- inferior to bladder
- wraps around prostatic urethra
produces secretion:
- ~30% of semen
- slightly acidic, milky fluid
- contains PSA: prostate-specific antigen
- contributes to sperm activation, viability and motility

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7
Q

describe the bulbourethral glands

A
  • two glands located in the urogenital diaphragm
  • open into spongy/penile urethra
  • contribute ~5% of semen volume
  • secretions lubricate and neutralise acidity in urethra prior to ejaculation
  • last 5% of semen is made of spermatozoa
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8
Q

what is a vasectomy?

A
  • surgical method of sterilisation in males
  • cut the ductus deferens (cut ends tied or cauterised)
  • this has no effect on seminal fluid a this fluid doesn’t contain sperm
  • it would reduce semen volume as sperm is part of this though
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9
Q

describe gametogenesis

A

formation of the gametes (sex cells)
- spermatogenesis in males
- oogenesis in females
under hormonal control
occurs via mitosis and meiosis
- cells need to be haploid (23 chromosomes)

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10
Q

brief overview of meiosis

A
  • same basic process in males and females
  • original cell has 46 chromosomes (diploid/2n)
  • two cycles of cell division to produce gametes (23 chromosomes = haploid/n)
  • meiosis I: 2 haploid cells produced from one original diploid cell
  • meiosis II: each cell produced from meiosis I divides to produce two haploid cells with 23 chromosomes
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11
Q

describe spermatogenesis

A
  • formation of the male gamete
  • the process by which spermatogonia are transformed to mature spermatozoa (sperm)
  • occurs continuously from puberty onwards
  • occurs in the seminiferous tubules
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12
Q

what occurs in the first stage of spermatogenesis?

A
  • spermatogonia divide by mitosis into 2 daughter cells (diploid - 46 chromosomes)
  • one spermatogonium (type A) stays at the basement membrane of the seminiferous tubule - this is important because they are the steam cells so one has to stay behind to produce more
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13
Q

what occurs in the second stage of spermatogenesis?

A
  • the second spermatogonia (type B) differentiates into a primary spermatocyte (diploid), which undergoes meiosis I
  • form 2 secondary spermatocytes (haploid - 23 chromosomes, have the right number of chromosomes but too much DNA)
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14
Q

what occurs in the third and final stage of spermatogenesis?

A
  • these undergo meiosis II to form spermatids (haploid)
  • spermatids differentiate into spermatozoa with a head, body and tail via spermiogenesis
  • spermiogenesis is the process of differentiation from a circular cell to one with a tail and stuff, it is part of spermatogenesis
  • spermatozoa released into lumen, then transported down the tuble by fluid
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15
Q

what are some key structural changes that occur during spermiogenesis

A
  • acrosome starts to form (the triangle pointy bit, contains enzymes that help it enter the oocyte)
  • tail forms (flagella)
  • excess cytosol with extra organelles comes away and is disposed of
  • lots of mitochondria to provide these cells with lots of energy
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16
Q

what are the reproductive hormones of the male reproductive system?

A

GnRH:
- gonadotropin releasing hormone produced by the hypothalamus
- released and transported to the anterior pituitary
LH:
- luteinising hormone (a gonadotropin) produced by the anterior pituitary
FSH:
- follicle stimulating hormone (a gonadotropin) produced by the anterior pituitary

gonadotropin = hormone that acts on the gonads

17
Q

what are the male hormones?

A

Inhibin:
- from nurse (Sertoli) cells
- these cells are found within the seminiferous tubules
Testosterone:
- produced by interstitial endocrine (Leydig) cells
- these cells are found outside of the seminiferous tubules
- type of androgen
- group of steroid hormones
- responsible for male characteristics (maturation of sex organs, spermatogenesis, secondary sex characteristic, libido)
- synthetic androgens (steroids) - therapeutic purposes

18
Q

describe the negative feedback loop for the male hormones in their reproductive system

A
  • GnRH stimulates the release of LH and FSH
  • LH stimulates production of testosterone (interstitial endocrine [Leydig] cells)
  • FSH and testosterone control spermatogenesis
  • FSH stimulates Inhibin production (nurse [Sertoli] cells)

Negative feedback:
- inhibin surpresses FSH
- testosterone suppresses LH and GnRH