reproductive system (Female) Flashcards
Describe the endocrine glands that control reproduction and regulation of gonadotrophin secretion
The reproductive system is controlled by the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are produced by the pituitary gland. Gonadotropin release is controlled by the hypothalamic hormone gonadotropin-releasing hormone (GnRH).
Two main functions of gonads
- Produce gametes
2. Produce reproductive hormones
Progesterone
is the major steroidal hormone of the corpus luteum and of the placenta. Associated with the preparations for pregnancy and its maintenance
Sex determination
commitment of the bipotential gonad to a testis or an ovary
Sex differentiation
The phenotypic development of genital structures due to the action of hormones produced by the gonad
The Sex-determining factor
The Sex-determining Region on the Ychromosome (known as the SRYgene) provides the pathway for testes to develop. The presence of a testis determines the sexual fate of the embryo, against the basic feminine trendIn the absence of SRY, the embryo develops into a female.
Sex differentiation : Internal genitalia
female and male
Müllerian duct = Female
Wolffian duct = Male
Development of the male internal
reproductive system.
1. Male differentiation Müllerian duct regression occurs under the control of Anti-müllerian hormone (AMH) secreted by Sertoli cells.
- Testosterone secreted by the testis
(Leydig cells) actively maintain the
Wolffian ducts. - The Wolffian ducts develop into the
epididymis, vas deferens and seminal
vesicles. - The testis descends from its internal
position to the scrotum, usually after
the 7th month
Development of the female
internal reproductive system.
- Female differentiation
The Wolffian ducts begin to
regress slowly from about 10
weeks.
2. The Müllerian ducts persist and develop to give rise to the uterine (fallopian) tubes, uterus, cervix, and upper vagina.
Development of the Female external
genitals
Female differentiation The urethral folds and labioscrotal swellings remain separate, thus forming the labia minora and majora The genital tubercle (glans area) forms the clitoris.
Development of the male external
genitals
Male differentiation Fusion of the urethral folds enclosing the urethral tube forming the shaft of the penis Labioscrotal swellings fuse in the midline forming the scrotum The genital tubercle (glans area) expands forming the glans penis