Reproductive system Flashcards
Upon ovulation , the oocytes is released into the?
abdominal cavity
Cell Cycle phases
Interphase, G0, G1, S, G2, M
G0 stage
the cell is living and serving its function ( i.e nerve cells)
G1 stage
- Grow in size
- Create organelles
- DNA quality control checkpoint by p53
S phase
- Replication
- 46 chromosomes present
G2 phase
- DNA and organelle quality control checkpoint by p53
M phase
- 4 phases within
- Include cytokinesis.
Control of the cell cycle
- Cdk and cyclin complex forms
- Cdk phosphorylate Transcription factors
- Transcription factors initiate transcription
Cancer
- Result of deranged cycle regardless of quality or quantity.
- Caused by mutated p53
- Metastasis is a result of blood vessel formation
Mitosis Consist of 4 phases
Prophase
Metaphae
Anaphase
Telophase
Prophase
- Chromatin condensation
- Centrioles polarize , localize at centrosome, form spindle and kinetochore fibers, express asters that anchor them to cell membrane
- Nuclear membrane dissolves
- Kinetochore appear on centromere.
Metaphase
- Chromosome aligns at metaphase plate (equatorial plate)
- Kinetochore fibers attach to kinetochore.
Anaphase
- sister chromatids split
- Shortening of kinetochore fibers.
Telophase and cytokinesis.
- Spindle disappears
- Nuclear membrane reforms
- Chromosomes uncoil
- Separation of cytoplasm and organelles
Meiosisproduces four unidentical cells
Why?
crossing over , random fertilization, and independent assortment of chromosomes (Mendel’s law).
other name for Meiosis
Reductional division
other name for mitosis
Equatorial division
Sex-linked disorders
- Males are hemizygous; expressing any defects
- Females are homozygous; carrier of the defect.
Y chromosome
- Contains SRY gene; formation of male gonads.
seminiferous tubules
Sperm production and nourishment by Sertoli cells