Reproductive System Flashcards
What are examples that show that the reproductive system isn’t essential in maintaining homeostasis?
- getting pets fixed
- Hysterectomy (ovaries/uterus removed)
- Castration: 2 young boys had testes removed to keep voice high-pitched, both lived past 70
Describe the testis
= site of hormone and sperm production
- cased in tough capsule (for protection)
- located inside the scrotum (which is outside of the body in humans)
- Being outside of the body allows
- Cooling (testis must have a temp. lower than body)
- Cremaster muscles can elevate it to regulate temp.
Function of the VAS DEFERENS
= muscular tube that helps expel/propel sperm
(can also store some sperm)
- cut and tied off in vasectomy procedures
Function of the EPIDIDYMUS
- sperm storage (can store over a month’s supply)
- site of maturation
Function of the SEMINIFEROUS TUBULES
- make sperm; 100s packed in together
- produce hormones (mainly testosterone)
- 3 components: Sertoli cell, Leydig cell, Spermatocytes
Function of SERTOLI CELL
- support and regulate spermatogenesis (produce substances that help)
- makes up the wall of the tubule
Function of LEYDIG CELL
- produces testosterone (which diffuses into sertoli and nearby blood vessels after)
- found outside of the tubule, near blood vessels
Function of SPERMATOCYTES/SPERMATOGONIA
= sperm cells
- populate the seminiferous tubules prior to birth, start dividing once sufficient testosterone (aka at puberty)
Describe Spermatogenesis
- initiated at puberty (point where sufficient testosterone)
Spermatogonia (diploid) –> 1˚ spermatocytes –> 2˚ spermatocytes
–> spermatids (haploid) –> spermatozoa
Describe Testosterone and its properties
- Steroid hormone (hydrophobic, lipophilic … therefore, can cross membranes easily)
- Made from cholesterol (= the precursor)
- Androgen-Binding protein –> needs to a protein to transport it to thru blood and make it soluble
- Intracellular receptors that allow testosterone to bind and promote/inhibit transcription –> since it works at this DNA level, takes longer for effects to take place since must make proteins from scratch
- Precursor for DHT and estradiol
- Regulated by the hypothalamic-anterior pituitary feedback pathway
Functions of Testosterone in males
- negative feedback
- spermatogenesis
- secondary sex characteristics
- anabolic reactions (increase muscle mass)
What are the side effects of exogenous testosterone?
It will increase muscle mass but….
- shuts off LH/Leydig/testosterone production
- decreases sperm count
- results in testicular atrophy
Semen (other secretions + their origins)
Seminal Vesicle: 60%
- fructose –> energy source
- clotting proteins (alkaline) –> semen clots to retain in female for a short period of time
Prostate Gland: 30%
- citric acid –> energy source
- enzymes (slightly acidic) –> various functions, one stops clotting so it can move through female
Bulbourethral Gland: minor concentration
- mainly mucus (alkaline) –> protects sperm from acidic environment of vagina
Describe Prostate Enlargement/Prostate Cancer
- urethra passes right through the prostrate, therefore when the prostate is enlarge it prevents the urethra from draining and you from peeing
- Diagnosis: digital rectal exam to check for size
Define OVARIES
= site of production of sex hormones and reproductive cells
- 2 paired ovaries suspended on other side of the uterus (in upper pelvis)