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BMSc > Reproductive Science > Flashcards

Reproductive Science Flashcards

1
Q

Name the three main types of hormone

A

steroid
peptide
tyrosine derivative

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2
Q

which hormones are produced from anterior pitutary gland

A

growth hormone,
luteinising hormone
follicle stimulating hormone
thryoid stimulating hormone
ACTH
prolactin

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3
Q

what hormones are produced form the posterior pituitary

A

oxytocin
ADH

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4
Q

what is the role of kisspeptin

A

potent stimulator of GnRH secretion

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5
Q

what is the relationship between dopamine and prolactin

A

prolactin is under tonic inhibtion by hypothalamic dopamine

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6
Q

what is the target cell of the LH in males

A

Leydig cells

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7
Q

what is the target cell of LH in females

A

theca cells

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8
Q

what increases the expresson of steoridogenic acute regulatory potein (StAR)

A

LH

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9
Q

what is the role of StAR

A

promotes transfer of cholesterol to the inner mitochondrial membrane - so initiates steroidogenesis

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10
Q

what is cholesterol converted to in the inner mitochrondrial membrane by action of P450scc

A

Pregnenolone

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11
Q

in whihc cells is testosterone produced

A

leydig cells

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12
Q

what cells are found adjacent to seminiferous tubules

A

leydig cells

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13
Q

in which 3 locations does oestorgen synthesis occur in females

A

granulosa cells
theca cells
corpus luteum

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14
Q

what hormone controls the expession of aromatase

A

FSH

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15
Q

what marks day 1 of the menstrual cycle

A

bleed

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16
Q

define oligomenorrhoea

A

reduction in frequency of periods to less than 9/year

17
Q

define primary amenorrhoea

A

failure of menarche by age 16

18
Q

define secondary amenorrhoea

A

cessation of periods for more than 6 months in someone who has previously menstruated

19
Q

at what age can someone be described as having premature ovarian failure

A

under 40

20
Q

define primary hypogonadism

A

problem with the ovaries

21
Q

define secondary hypogonadism

A

problem with hypothalamus or pituitary

22
Q

what criteria is used for PCOS

A

rotterdam criteria

BMSc (1 decks)

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