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SBM 302 MT2 LVL2 > Reproductive Pharmacology > Flashcards

Reproductive Pharmacology Flashcards

1
Q

What is the mechanism of action of testosterone?

A

Binds to androgen receptors to regulate gene expression

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2
Q

What is the function of 5α-reductase inhibitors?

A

Prevent the conversion of testosterone to DHT

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3
Q

What is the mechanism of action of Clomiphene?

A

Blocks estrogen receptors, increasing GnRH secretion

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4
Q

What is the function of Flutamide?

A

Androgen receptor antagonist for prostate cancer

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5
Q

What is the primary function of estrogen in oral contraceptives?

A

Suppresses FSH to prevent follicle development

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6
Q

What is the function of progestin in oral contraceptives?

A

Thickens cervical mucus and suppresses ovulation

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7
Q

What is the mechanism of action of Danazol?

A

Suppresses the pituitary-ovarian axis by acting on androgen receptors

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8
Q

What is the clinical use of GnRH agonists?

A

Prostate cancer, breast cancer, endometriosis, fibroids

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9
Q

What is the function of GnRH antagonists?

A

Block GnRH receptors to suppress LH and FSH secretion

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10
Q

What is the role of hCG in pregnancy tests?

A

Detected in urine to confirm pregnancy

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11
Q

What is the function of depot medroxyprogesterone acetate (DMPA)?

A

Long-acting contraception by inhibiting ovulation

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12
Q

What is the mechanism of action of Aromatase inhibitors?

A

Block estrogen synthesis by inhibiting aromatase enzyme

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13
Q

What is the function of beta-agonists in labor?

A

Relax uterine muscles to delay contractions

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14
Q

What is the primary function of Oxytocin receptor antagonists?

A

Block oxytocin receptors to prevent contractions

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15
Q

What is the primary function of GnRH in assisted reproduction?

A

Prevents premature LH surge during ovarian stimulation

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16
Q

What is the major side effect of combined oral contraceptives?

A

Increased risk of thromboembolism

17
Q

What is the function of Letrozole?

A

Aromatase inhibitor for breast cancer and ovulation induction

18
Q

What is the function of Raloxifene?

A

Selective estrogen receptor modulator used for osteoporosis

19
Q

What is the function of Mifepristone?

A

Blocks progesterone receptors to induce abortion

20
Q

What is the function of Ulipristal acetate?

A

Selective progesterone receptor modulator used for emergency contraception

SBM 302 MT2 LVL2 (34 decks)

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