Reproductive Hormones

Question 1

LH

Answer 1

Luteinizing Hormone

Females: induces ovulation and development of corpus luteum to produce progesterone.

Males: produce testosterone from Leydig cells.

Question 2

FSH

Answer 2

Follice-stimulating Hormone

Female: stimulate the growth of immature ovarian follicles to produce estrogen.

Males: stimulate spermatogenesis and sertoli cells to produce ABPs.

Question 3

human Chorionic Gonadotropin (hCG)

Answer 3

Similar to LH, can also induce ovulation in the ovaries as well as testosterone production in the testes.

Used in Prepubertal Cryptorchidism (induce testicular descent)

Question 4

Alkylation of 17-alfa position of Testosterone

Answer 4

Allowed for administration of the hormone.

Examples: Methyltestosterone, Fluoxymesterone and Oxymetholone. (HEPATOTOXIC)

Question 5

Vasopressin Receptor Antagonists

Answer 5

Conivaptan and Tolvaptan

FDA-approved for the treatment of hyponatremia associated with CHF and SIADH.