Reproductive Health Flashcards

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1
Q

PTEN Gene (phosphate and tension homolog) is inactivated in what disease. What does this predispose one too?

A

Cowden’s Disease ( multiple hamartoma syndrome) and it can cause endometrial hyperplasia and Ca.

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2
Q

What imaging is best for epididymitis?

A

U/S

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3
Q

What is the treatment of Endometriosis?

A

Combined BC pills

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4
Q

What non oral modification should be considered in children with cleft palate?

A

Ear tubes due to the risk of otitis media

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5
Q

Drug that can cause adenocarcinoma of the vagina with in utero exposure?

A

Diethylstilbestrol

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6
Q

What complication might a Linguine sign suggest?

A

Ruptured breast implant

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7
Q

What are physiological risks of Breast ca. (4)

A

Female, nulliparis, early menarche, late menopause

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8
Q

Adenocarcinoma of the nipple

A

Paget’s Disease

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9
Q

Solid lesions in the duct that present with clear or bloody nipple discharge

A

Intra-ductal papillomas

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10
Q

Treatment for ______ could possibly cause self limiting hypotonia in an infant?

A

Pre-eclampsia.

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11
Q

3 cancers that commonly metastasize to the leptomeninges of the brain

A

Breast, Lung, Melanoma

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12
Q

TRX for ectopic pregnancy

A

methotrexate

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13
Q

Septic abortion trx??

A

IV ABx + cervical dilation and curettage

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14
Q

Pregnancy what happens hormonally?

A

Syncytiotrophoblast produces human chorionic gonadotropin (hCG), which stimulates progesterone production by the corpus luteum.

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15
Q

Mullerian agenesis

A

Failure to develop upper vagina and uterus. Blind pouch

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16
Q

Dx for Hirschsprung retention

A

rectal biopsy showing lack of ganglionic cells

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17
Q

What infection can increase risks of ectopic pregnancy

A

chlamydia or any Pelvic inflammatory disease that damages fallopian tubes.

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18
Q

first line treatment for nonclassical adrenal hyperplasia

A

glucocorticoids

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19
Q

vaginismus and trx:

A

pain with penetration, due to pelvic floor spasm. Desensitization theory

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20
Q

Aplasia cutis congenita?

A

congenital focal absence of skin. Assoc with trisomy 13

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21
Q

btw what layers does an epidermal go

A

Ligmentum Flavum and Dura mater

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22
Q

Breastfeeding vs Breastmilk jaundice?

A

3-5 day onset compared to 1-6weeks

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23
Q

when to screen for gestational DM?

A

late 2nd trimester (24-28wks)

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24
Q

imperforate hymen in a newborn description?

A

Imperforate hymen presents in neonates as a bulging blue domed, translucent membrane at the level of the vaginal introitus

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25
Q

placental abruption symptoms and risks?

A

Acutely Painful abdomen. Bleeding. low amplitude but rapid contractions. risks: Trauma, cocaine

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26
Q

Staghorn calculi composition and associations?

A

struvite. Appears as calcifications surrounding the kidney after Proteus, Klebsiella, Pseudomonas, and Enterobacter UTI’s

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27
Q

Trichomoniasis infection in women symp?

A

vaginal and vulvar erythema, vaginal burning and pruritus, and foul, thin, yellow-green discharge. sometimes strawberry cervix.

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28
Q

Lichen plantus vs lichen sclerosis

A

Plantus in the vagina sclerosis in general vulvula region

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29
Q

at what time is penicillin given to a . GBS positive woman?

A

onset of labor

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30
Q

imperforate hymen diagnosis?

A

U/S

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31
Q

caudal regression syndrome is associated with what maternal risk factor?

A

Diabetes

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32
Q

class of medications given to delay labor?

A

beta 2 agonists

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33
Q

Asherman syndrome

A

Scarred uterus from gynecological surgeries leading to possible secondary amenorrhea

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34
Q

What drugs are given to help pass a inevitable abortion

A

misoprostol and oxytocin

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35
Q

Lynch syndrome and associated cancers

A

Hereditary nonpolyposis colorectal cancer

ASSOC with: colon, ovarian, endometrial, and breast cancers

36
Q

common palsy from shoulder dystocia

A

Erb Duchenne palsy C5 and C6 nerve roots

37
Q

What tumor marker to track progress of cancer trx on ovarian dysgerminoma?

A

LDH

38
Q

What tumor marker to track progress of cancer trx on ovarian epithelial tumor?

A

Ca-125

39
Q

Treating Gonorrhea and chlamydia

A

Gonorrhea- ceftriaxone Chlamydia= doxycycline or azithromycin

40
Q

Squamous cell carcinoma in an area where semen goes is caused by what infection??

A

HPV

41
Q

Tubo ovarian abscess trx?

A

Occurs after PID. IV Cefoxitin and PO or IV doxycycline and if no improvement in 48hrs drain the abscess

42
Q

Drug for woman trying to conceive with PCOS

A

clomiphene.

43
Q

Blind Pouch, no tubes or uterus, normal hormones 46XX

A

Mullerian agenesis

44
Q

asymmetrical uterus and chronic pain + bleeding classis for

A

fibroids

45
Q

Hot flashes trx

A

venlafaxine

46
Q

Postpartum blood loss

A

500cc for vaginal or 1000cc for C-section

47
Q

Bethanechol vs Oxybutynin

A

Oxybutynin for spastic bladder

Bethanechol for flacid

48
Q

Bladder cancer diagnosis

A

cystoscopy

49
Q

hyperemesis gravidarum what you do

A

Correct electrolyte abnormalities and screen for moles with Beta HCG then do U/S to double check

50
Q

vaginismus trx

A

kegels and dilators to relax pelvic floor

51
Q

danger of pregnancy over 41 wks?

A

oligohydramnios

52
Q

epigastric pain in pregnancy think…

A

Gerd of Capsular stretch from eclampsia

53
Q

During labor uterus becomes boggy and soft? What do

you do?

A

Crash C section

54
Q

Best initial test for fetal anemia

A

middle cerebral artery doppler

55
Q

hx of fetal loss during 2nd trimester increases risk for what?

A

cervical insufficiency

56
Q

Hypothyroidism during pregnancy counseling

A

Levothyroxine dose will need to increase (as estrogen increases so does Thyroid binding globulin effectively decreasing active dose.)

57
Q

Ferning on the slide and thin stringy vaginal mucus. What stage of Menstrual cycle

A

Ovulation

58
Q

What do you do if baby needs more time and no ROM?

A

Tocolytics+ steroids

59
Q

tachysystole?

A

5+ contractions every 10 min

60
Q

tachysystole trx

A

terbutaline 1st line tocolytic (beta 2 agonist) side effect is pulmonary edema

61
Q

adequate accelerations

A

15 up in 15 seconds and 2 in 20 min

62
Q

Prom?

A

18 hours since water broken. treat with amp and gent

63
Q

Clomiphene?

A

induces ovulation

64
Q

Kleihauer Berke test

A

used to look for compatibility issues and dose rhogam

65
Q

Proteinuria

A

Pr/Cr greater than 0.3 or 300mg/day

66
Q

School of fish on histology

A

chancroid

67
Q

Derm manifestations of pregnancy

A
  1. Intrahepatic cholestasis- Itching at night palms and soles
  2. pruritic urticarial plaques and papules
  3. Herpes stations
68
Q

Acute fatty liver of P

A

n/ v, LFT’s, caused by mitochondria dysfunction

69
Q

Magnesium toxicity sign

A

hyporeflexia

70
Q

prematurity supplements

A

<32wks: Mg, tocolytics, steroids
32-34: tocolytics + steroids
34-37: steroids

71
Q

Vaginal delivery for HIV mom

A

viral load under 1000/ml

72
Q

ureteral diverticulum vs vesicovaginal connection

A

diverticulum is intermittent leaking while a connection is constant

73
Q

Short cervix no history of preterm?

A

projesterone to prevent rupture

74
Q

Contraindicated med in Myasthenia Gravis

A

Magnesium

75
Q

treatment for lichen sclerosis

A

clobetasol

76
Q

Lichen Planus

A

50-60y/o

Itchy. May be either erosive with white borders or papulosquamous with a purple hue

77
Q

Pre eclampsia and crackles

A

pulmonary edema due to vasospasm causing high resistance of peripheral vessels so fluid backs up in the lungs

78
Q

ovulation induction treatments, ascites, distention and bilateral enlarged ovaries?

A

Ovarian hyperstimulation syndrome

79
Q

Diethylstilbestrol in utero exposure?

A

clear cell vaginal adenocarcinoma

80
Q

Tamoxifen adverse effects

A

VTE
Increased endometrial cancer risk
Hot flashes

81
Q

postmenopausal bleeding =

A

bx or u/s

82
Q

Pylo in pregnancy treatment

A

IV abx

83
Q

Preeclampsia feared complication

A

CVA

84
Q

Methyergonovine contra indication

A

HTN disorders due to vasoconstrictor

85
Q

Amino infusion use

A

Variable decelerations to take pressure off umbilical cord

86
Q

In rapid virilization what does high T and normal DHEAS tell you

A

Some type of ovarian source likely sertoli leydig tumor

87
Q

Treatment for high risk of pre eclampsia ?

A

Asa at 16 weeks until delivery