reproductive endocrinology Flashcards
1
Q
Causes of premature menopause
A
Autoimmune or idiopathic (association with other autoimmune diseases)
Turner syndrome
Chemotherapy esp cyclophosphamide
Familial
2
Q
Biochemical tests in premature menopause
A
FSH over 20 IU/L generally is diagnostic
3
Q
Complications of Turner syndrome
A
Autoimmune thyroid disase Coeliac type 1 DM Metabolic syndrome aortic stenosis, coarctation, congenital heart disease IHD osteoporosis neurocog and behavioural horseshoe kidney hearing loss
4
Q
Features of turners
A
short
ovarian dysgenesis–>primary OR SECONDARY amenorrhoea, infertility
Webbed neck, breast plate, increase carrying angle of the elbows
5
Q
premature menopause definition
A
before 40
6
Q
Causes of secondary amenorrhoea
A
hypothalamic amenorrhoea: stress, exercise, wt loss, medical illness Pituitary: hyperprolactinoma, sheehan Thyroid: high or low Adrenal: CAH, cushings, addisons Ovarian: PCOS, premature menopause Uterine: Asherman's syndrome
