Reproduction Flashcards
What are the types of mammary gland diseases we will see?
Tumors, hyperplasia, carcinoma
How many pairs of mammary glands do dogs have?
5
T/F: Mammary tumors are the most common neoplasm in intact female dogs
True. 70%
T/F: Mammary tumors in male dogs is common
False.
How often are mammary tumors malignant in a dog?
50%
T/F: The glandular area is most commonly the origin of neoplasm
True
Which glands of the mammary are most commonly affected?
4 and 5
T/F: Watch and wait is the best way to deal with mammary tumors
False
What do you do to pre-op a CMT?
bloodwork, radiographs (for mets), ultrasound/imaging
What is the only way to differentiate a malignant from a benign mammary tumor?
Biopsy
T/F: you want to perform an incisional biopsy for diagnostic purposes
False. Excisional
What are the criteria of malignancy (COM)?
Rapid growth, size, fixation in skin, circumscribed, ulceration/inflammation
How wide do you want to make your marginal excision?
2-3 cm
T/F: A benign mass can become a malignant one
True
What is a lumpectomy?
Removal of a small solitary mass with 1 cm margin
What should you do if the mass suited for a lumpectomy is in the middle of a gland?
Remove the entire gland (simple mastectomy)
When would you perform a simple mastectomy?
When there is a solitary mass 1-2 cm within the gland
How wide are your margins in a simple mastectomy?
2-3 cm
What shape is your incision for a simple mastectomy?
Elliptical
What would have to happen is the mass is greater than 2 cm, has multiple COM, or the 2-3 cm for a simple mastectomy is not enough?
Removal of multiple glands
What glands are to be removed, if a mass affects glands 1 and/or 2?
Glands 1-3
What glands are to be removed, if a mass affects glands 4 and/or 5?
Glands 3-5
What lymph node is removed along with gland 5 in a regional mastectomy?
Superficial inguinal lymph node
What are the chances a dog with a mass on one side will have recurrence on the other side?
60%
If gland 3 is affected, what do you do?
Chain mastectomy
How long do you wait to perform another chain mastectomy after the first one?
4-6 weeks
What is the mean survival time of a malignant CMT with no metastasis?
1-2 years
What are the most common sites of metastasis with CMT?
Lung, liver, bone, lymph node, kidney, spleen
What can you do to prevent CMT?
Spay your dog
What is the cutoff age for prophylactic spay for CMT?
2 years
If you had to do both a spay and a mastectomy, which would you do first?
Spay
How do you treat canine mammary hyperplasia?
You don’t. It’s physiologic (progesterone) and will regress on its own
What signs do you see with inflammatory carcinoma?
Edema, erythema pain, multiple firm glands
What is the mean survival time for inflammatory carcinoma?
<1 month
What surgery do you use to treat inflammatory carcinoma?
Not recommended to do surgery
How might you treat inflammatory carcinoma?
NSAIDs may help
T/F: Feline mammary tumors are more common than canine
False
T/F: Feline mammary tumors are usually benign
False
What is usually the type of cancer from a mammary tumor?
Adenocarcinoma
T/F: Male cats get mammary tumors more often than male dogs
True
How many pairs of mammary glands do cats have?
4
When would you not want to perform surgery on a mammary tumor?
If metastasis is present
What surgery do you do for every feline mammary tumor?
Chain mastectomy, regardless of number or size
What is the mean survival time for a feline mammary tumor that is <2 cm? >3 cm?
3 years; 6 months
What molecule is fibroadenomatous hyperplasia of the mammary gland dependent on?
Progesterone
What age of cat most commonly has fibroadenomatous hyperplasia of the mammary gland
<2 years
How can you definitively diagnose fibroadenomatous hyperplasia in a cat?
Histopathology
How would you treat fibroadenomatous hyperplasia of the mammary tumor?
Spay, with a flank approach
T/F: Nonfunctional ovarian cysts are typically incidental findings
True
What is the best way to deal with a nonfunctional or functional ovarian cyst?
surgical excision with histopathology
What type of functional ovarian cyst is most common?
follicular cyst, estrogen
How old are the animals when affected by a functional ovarian cyst?
Dogs <3
Cats <5
What hormone is dominant during proestrus and what happens to the dog?
estrogen, enlarged vulva, attractive to males
What hormone surges and activates ovulation during estrus?
Luteinizing hormone
What hormone is dominant during diestrus?
Progesterone
What would you see with a ovarian tumor with stromal origin?
Pyometra
How do you diagnose an ovarian tumor?
Radiographs, ultrasound
T/F: Metastasis is common with ovarian neoplasia
false
What causes ovarian remnant syndrome?
Surgical error. Ovarian tissue is left behind
T/F: Ectopic tissue is reported in dogs
False. Reported in cats
How do you diagnose ovarian remnant syndrome?
Cytology of vagina while in heat, hormone assays
What is an ovariectomy and is it an acceptable form of spay?
Removal of only the ovary. It is acceptable
When would you perform a unilateral ovariectomy?
To treat cystic disease only
What forms after ovulation and what does that make?
Corpus luteum makes progesterone
What does progesterone do to the endometrial glands?
Increases number and secretion
What can occur with abnormal progesterone exposure?
Cysts, neoplasia, remnants
What is cystic endometrial hyperplasia caused by and what is it filled with?
excess progesterone.
filled with aqueous material, mucus, or blood
How do you diagnose cystic endometrial hyperplasia?
Ultrasound
T/F: Cystic endometrial hyperplasia is a medical emergency
False.
How do you treat CEH?
Spay
What hormone causes pyometra?
Progesterone via uterine secretions
What is most common bacteria isolated in pyometra?
E. coli
How do bacterial toxins cause PU/PD? know this
Inhibition of ADH
If an intact female is sick, what is immediately on your rule out list?
Pyometra
What will you see on PE for a dog with pyometra?
fever, painful abdomen, vaginal discharge
What’s the CBC for a dog with pyometra?
left shift neutrophilia, thrombocytopenia, hypoalbuminemia, mild cholestasis