replicación Flashcards

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1
Q

Características de la replicación:

A
  • Bidireccional
  • Semiconservadora
  • Replicación multifocal (eucariota)
  • Continua y discontinua
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2
Q

A qué se refiere semiconservadora?

A

1 hebra siempre se estará manteniendo

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3
Q

Cómo es la replicación continua?

A

5’ a 3’

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4
Q

Qué deja la replicación descontinua?

A

Fragmentos de Okazaki

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5
Q

Rompe los puentes de hidrógeno causando superenrrollamiento:

A

Helicasa

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6
Q

Evita de la formación de puentes de hiodrógeno:

A

RPA
Proteína de unión a cadena sencilla

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7
Q

Sintetiza primers y proporciona extremo 3’:

A

Primasa

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8
Q

Cortan y forman enlaces fosfodiester:

A

Topoisomerasa

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9
Q

Retira los primers en hebra continua

A

RNAsa H1

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10
Q

Remueve los primers en hebras discontinua

A

Endonucleasa FLAP1

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11
Q

Pone enlaces fosfodiester entre nucleótidos contiguos:

A

Ligasa

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12
Q

Copia telómeros

A

telomerasa

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13
Q

Mantiene a todas las enzimas unidas al ADN hasta que termine de replicarse:

A

Antígeno de proliferación celular (PCNA)

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14
Q

ADN polimerasa alpha

A

pone primers con la primasa

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15
Q

ADN polimerasa delta:

A

elongación de las hebras de ADN discontinuas

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16
Q

ADN polimerasa epsilon

A

elongación de hebras de ADN continuas

17
Q

ADN polimerasa beta

A

Repara errores

18
Q

ADN polimerasa gamma

A

única que participa en replicación de ADN mitocondrial

19
Q

¿cuál es el punto origen?

A

adenina timina