Renal Tubular Acidosis Flashcards
1
Q
Finding on ABG
A
Hyperchloraemic metabolic acidosis
Normal anion gap
2
Q
Where does type 1 happen
A
Distal tubule
3
Q
Why does type 1 happen
A
Inability to generate acid urine (secrete H+) in distal tubule
4
Q
Complications of type 1 (2)
A
Nephrocalcinosis
Renal stones
5
Q
Causes of type 1 (6)
A
Idiopathic RA SLE Sjogrens Amphotericin B toxicity Analgesic nephropathy
6
Q
Which cause hypokalaemia
A
1, 2 and 3
7
Q
Which cause hyperkalaemia
A
4
8
Q
Where does type 2 happen
A
Proximal tubule
9
Q
Why does type 2 happen
A
Decreased HCO3- reabsorption in proximal tubule
10
Q
Complication of type 2
A
Osteomalacia
11
Q
Causes of type 2 (6)
A
Idiopathic Fanconi syndrome Wilson’s disease Cystinosis Outdated tetracyclines Carbonic anhydride inhibitors
12
Q
Where does type 3 happen
A
Mixed
13
Q
What causes type 3
A
Carbonic anhydrase II deficiency
14
Q
Where does type 4 happen
A
Collecting duct
15
Q
Why does type 4 happen
A
Reduction in aldosterone —> reduction in proximal tubular ammonium excretion
