renal stones Flashcards
what is the presentation of renal stones?
severe loin-to-groin pain
what is the main composition of renal stones?
calcium oxalate
which type of stone does crohns predispose to?
calcium oxalate
what are the risk factors for renal stones?
Dehydration
Previous kidney stone
Stone-forming foods
Genetic: cystinuria (Dent’s disease; cysteine stones), renal tubular acidosis (calcium phosphate stones)
Systemic disease: Crohn’s disease (calcium oxalate stones)
Metabolic: hypercalcaemia, hyperparathyroidism, hypercalciuria (calcium stones)
Kidney disease-related: medullary sponge kidney, AD polycystic kidney disease
Drugs: loop diuretics and acetazolamide can cause calcium stones; protease inhibitors (HIV medication) cause radiolucent stones
Exposure: cadmium or beryllium
Other: gout and ileostomies (uric acid stones)
what are examples of stone forming foods?
chocolate, rhubarb, spinach, tea, and most nuts are high in oxalate, and colas are high in phosphate
what type of stones are formed in Dents disease?
cystine
what type of stones are formed in renal tubular acidosis?
calcium phosphate stones
which types of stones are present in gout?
uric acid stones
what is an important differential to rule out when suspecting renal stones?
AAA especially in the elderly with new onset flank pain and no history of stones
what is the gold standard diagnostic imaging?
non contrast CTKUB within 14 hours
what is the management for kidney stones?
< 5 mm watchful waiting and conservative management with antiemtics like cyclizine and NSAIDS like IM diclofenac
> 5mm= surgery
- lithotripsy
- ureteroscopy
- percutaneous nephrolithotomy
which stones are associated with infection?
struvite-> produced by bacteria
what is the inheritence of cystinuria?
autosomal recessive-> leads to formation of cystine stones
which stones are not visible of XRAY?
uric acid stones
what are some lifestyle measures for reccurrent stone formers?
- increase oral fluid intake (2.5 – 3 litres per day)
- Add fresh lemon juice to water (citric acid binds to urinary calcium reducing the formation of stones)
- Avoid carbonated drinks (cola drinks contain phosphoric acid, which promotes calcium oxalate formation)
- Reduce dietary salt intake (less than 6g per day)
- Maintain a normal calcium intake (low dietary calcium might increase the risk of kidney stones)