Renal Regulation Flashcards
Afferent arteriole
Blood enters the capillaries if the nephron
Glomerulus
Located in the Bowman Capsule
Renal Blood flow
1200 mL/min
Glomerular Filtration
Controlled by hydrostatic pressure and oncotic pressure
Feedback mechanism of renin-angiotensin-aldosterone system (RAAS)
Shield of Negativity
Repels molecules with a negative charge - albumin
RAAS regulates
Flow of blood to and within glomerulus
Responds to changes in blood pressure and plasma sodium content
Juxtaglomerular apparatus
Maintains the glomerular blood pressure at a relatively constant rate
Macula densa
Located in the distal convoluted tubule
Monitors blood pressure and sodium content
Renin
Enzyme produced by juxtaglomerular cells
Reacts with bloodborne substrate angiotensinogen
Angiotensin I
Product of renin reacting with angiotensinogen
Passes through lungs
Angiotensin II
Product of angiotensin-converting enzyme (ACE) and angiotensin I
Corrects renal blood flow through vasodilation of afferent arterioles and constriction of efferent arterioles
Stimulates reabsorption of NA and H2O in PCT
Triggering release of NA-retaining hormone aldosterone
Proximal Convoluted Tubule (PCT)
Active reabsorption of glucose, amino acids, and salts
Passive reabsorption of water and urea
Secretion of organic acids and bases
Descending Loop of Henle
Passive reabsorption of water
Ascending Loop of Henle
Active reabsorption of NA
Passive reaborption of Urea and NA
Distal Convoluted Tubule (DCT)
Reabsorption of NA
Secretion of urea, uric acid, H+, NA+, and K+