Renal Physiology Flashcards
Most powerful trigger for ADH secretion
Increased plasma osmolarity
Effect of alcohol on ADH secretion
decrease ADH secretion, increase urine volume
Effect of ANP, BNP on urine secretion
Dec Na reabsorption
Effect of catecholamines on urine
Inc water reabsorption, inc Na reabsorption
Peritubular capillary hydrostatic pressure is decreased by
afferent and efferent arteriole vasocostriction
Peritubular capillary oncotic pressure is increased by
Plasma protein concentration and filtration fraction
Substance with the highest renal clearance
PAH > K > Creatinine > inulin > Urea > Na > Glucose, Amino acids
Rate at which substances are removed from blood in the kidneys
Renal clearance
Substance whose clearance is used to estimate GFR
inulin, BUN, Crea
Substance whose clearance is used to estimate renal blood flow and renal plasma flow
PAH
Substances filtered and partually reabsorbed have clearance __ than the GFR
less
Substances filtered and with net secretion have a clearance __ than the GFR
greater
Causes of High Anion Gap Metabolic Acidosis
Methanol Uremia DKA Paraldehyde, Propylene Glycol Iron, Isoniazid, Idiopathic Acidosis Lactic Acidosis Ethylene Glycol, Ethanol Salicylic Acid
Causes of Normal Anion Gap Metabolic Acidosis
Hyperalimentation Acetazolamide Renal Tubular Acidosis Diarhea Ureteroenteric Fistula Pancreaticoduodenal Fistula
pH that is compatible with life
6.8-8.0
Normal pH of the Gastric Hcl
0.8(1-3 Guyton)
H+ regulatory systems
body fluid buffer system(fastest)
respiratory center
kidneys
Renal regulation of Acid-base balance(3)
secretion of excess H+
reabsorption of filtered HCO3
production of new HCO3 by using Ammonia and phosphate
Vomiting will result in what acid-base abnormality
Metabolic Alkalosis(decreased ventilation)
COPD will result in what acid-base abnormality
Respiratory Acidosis
Pneumonia will result in what acid-base abnormality
Respiratory Alkalosis(increased ventilation)
Vomiting will result in what acid-base abnormality
Metabolic Alkalosis(decreased ventilation)
COPD will result in what acid-base abnormality
Respiratory Acidosis
Pneumonia will result in what acid-base abnormality
Respiratory Alkalosis(increased ventilation)