Renal Physiology Flashcards
What is urea?
A product of protein metabolism which is produced by the urea cycle in the liver. It is nontoxic and able to take up two NH3 molecules.
What is azotemia?
an increase of urea
What causes a renal azotemia?
Decrease in GFR causes urea to build up
What causes a Prerenal azotemia?
Eating, especially proteins.
What causes a Post Renal Azotemia?
UTI, Cystitis, Kidney infection
What is creatine?
The condensation product of two amino acids which then is acted upon by CK- Creatine Kinase. CK phosphorylates Creatine and it is now the storage form. (in muscles)
What is creatinine?
Creatine or Creatine Phosphate can auto oxidize and form creatinine which is a terminal degradation product.
What does BUN stand for?
Blood Urea Nitrogen
When will you see an increased BUN:Creatinine ratio?
With a Prerenal Azotemia; you will have an increase in urea, but creatinine stays the same.
Renal and Post Renal azotemias have a constant ratio because both values will change.
What endocrine function is the kidney responsible for?
Vit D production
Erythropoietin
<p>
| Interpret this picture.</p>
<p>
| As the molecular weight of proteins increases their filtration decreases.</p>
<p>
| What protein constitutes 80% of protein in urine?</p>
<p>
| Tamms-Horsefall Proteins</p>
<p>
What Pathological disease is associated with a decrease in GFR due to an inflammatory response of Bowman's capsule or anti glomerular basement membrane antibodies?</p>
<p>
| Glomerulonephritis</p>
<p>
| In what pathological condition will you see proteinuria, Edema, lipiduria, and loss of glomerular integrity?</p>
<p>
| Nephrotic Syndrome</p>
<p>
| What is Renal Vein Thrombosis also known as?</p>
<p>
| Hemolytic Uremic Syndrome</p>
