Renal Physiology Flashcards
There are two types of nephrons,what are they?
Superficial cortical and juxtamedullary
Peritibular capillaries in superficial cortical nephrons have a function of_?
Deliver nutrients to the epithelial cells,serve as blood supply for reabsorption and secretion
Peritubular capillaries in juxtamedullary nephrons have a function of _?
serve as osmotic exchangers for the production of concentrated urine
Volume contraction means
Decrease in ECF volume
Volume expansion means
Increase in ECF volume
Renal clearance equation:
C=[U]*V/[P]
where
C=clearance(ml/min)
[U]x=urine concentration of substance x(mg/ml)
V=urine flow rate(ml/min)
[P]x=plasma concentration of substance x(mg/ml)
Renal blood flow is _ % of cardiac output
25
Filtration fraction is _
Fraction of renal plasma flow filtered across glomerulus;0.2
Extraction coefficient _
E=(Pa-Pv)/Pa
where
Pa=concentration of certain substance in renal artery
Pv=concentration of certain substance in renal vein
Relationship of clearance and extraction coefficient
C=E*eRPF
E=F-R+S(EQUATION of tubular transport)
Amount excreted(E):UV
Filtered(F):PaGFR
R:reabsorbed
S:secreted
What is responsible in dilation and construction of afferent arteriole
Molecules lighter than _kD is freely permeable
70
Substances freely filtrated:
H2O,AA,Glu,Creatinine,small peptides(HCG)
Substances not filtered:
Albumin,hemoglobulin,myoglobulin
