Renal Path Flashcards
1
Q
What type of collagen forms the backbone of the glomerular basement membrane?
A
Type IV
2
Q
What does the macula densa detect?
A
Cl- delivery
3
Q
Nephrotic Syndrome features [5]?
A
> 3.5gm/day proteinuria
- Hypoalbuminemia (because lost in urine) (leads to loss of oncotic pressure which leads to edema)
- Edema
- Hyperlipidemia
- Lipiduria (specific for nephrotic disease)
4
Q
Nephritic Syndrome Features [3]?
A
- Hematuria
- Mild to moderate proteinuria
- Hypertension
5
Q
Nephrolithiasis clinical presentation [2]?
A
Renal colic (sudden, severe, sharp pain) Hematuria
6
Q
How do you calculate GFR?
A
Clearance = UV/P
U = urine concentration (mg/dl)
V = urine flow (ml/min)
P = plasma concentration (mg/dl)
7
Q
What creates the size barrier in the glomerular basement membrane?
A
the slit diaphragm.
