Renal Path Flashcards by Brendan LeBaron | Brainscape

Q

Deposits of neutrophils, IgG and complement

A

Post Infectious Proliferative GN

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Q

IF - Lumpy irregular pattern

A

Post Infectious Proliferative GN

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Q

Anti-GBM Ab mediated

A

Goodpasture

Type 1 RPGN

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Q

Antigen is NC1 domain of alpha 3 chain, type 4 collagen

A

Goodpasture

Type 1 RPGN

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Q

IF - linear IgG pattern

A

Goodpasture

Type 1 RPGN

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Q

Granular Ig and C3

Differentiated by IF

A

Immune complex: SLE or IgA

Type 2 RPGN

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Q

Crescentic proliferation and vasculitis, ANCA positive

A

Pauci Immune

Type 3 RPGN

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Q

Pulmonary hemorrhages

A

Goodpasture

Type 1 RPGN

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Q

ANA and ANCA negative, Low C3

A

Post Infectious Proliferative GN

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Q

Deposits of cartilage, blue hyaline

A

Multicystic Renal Dysplasia

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Q

Unilateral deformed kidney in younger patient

A

Multicystic Renal Dysplasia

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Q

Mutation coding for PKD1 - polycystin

A

Autosomal Dominant Polycystic Kidney Disease

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Q

Palpable masses in kidneys, bilateral

A

Autosomal Dominant Polycystic Kidney Disease

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Q

Associated with berry aneurysms

A

Autosomal Dominant Polycystic Kidney Disease

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Q

Patients die in infancy

A

Autosomal Recessive Polycystic Kidney Disease

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Q

Mutations coding for PKHD1 - fibrocystin

A

Autosomal Recessive Polycystic Kidney Disease

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Q

Numerous small cysts, sponge appearance

A

Autosomal Recessive Polycystic Kidney Disease

Q

Associated with congenital hepatic fibrosis

A

Autosomal Recessive Polycystic Kidney Disease

Q

Mutations coding for NHP1-9 Nephrocystin

A

Nephronophthisis - Medullary disease

Q

Small contracted kidneys, cysts at the corticomedullary junction

A

Nephronophthisis - Medullary disease

Q

Tubulointerstitial damaged, glomerulus spared

A

Nephronophthisis - Medullary disease

Q

Associated with retinitis pigmentosa

A

Nephronophthisis - Medullary disease

Q

Effacement of podocytes

A

MCD or FSGS

Q

Children puffy face

A

MCD

Q

Responds to steroids

A

MCD

Q

Selective proteinuria

A

MCD

Q

Foamy cells

A

MCD

Q

Segmental scarring

A

FSGS

Q

IF shows IgM and C3 in sclerotic areas

A

FSGS

Q

Non selective proteinuria

A

FSGS

Q

Not responsive to steroids

A

FSGS

Q

HIV infection

A

Collapsing FSGS

Q

KW nodule and arteriolar hyaline

A

Diabetic Glomerulosclerosis

Q

Complement forms MAC

A

M GN

Q

Immune against PLA2R - phospholipase A2 receptor

A

M GN

Q

IgM, granular deposits in sub epithelial space

A

M GN

Q

At risk for developing thrombosis

A

M GN

Q

Subendothelial immune deposits

A

MP GN

Q

Duplication of GBM

A

MP GN

Q

Lobular pattern of proliferation

A

MP GN

Q

Subendothelial C3 deposits

A

C3 GN / MPGN Type 2

Q

Dense deposit disease

A

C3 GN / MPGN Type 2