Renal Histology Flashcards
What are the basic components of the renal corpuscle?
Glomerulus, Bowman’s Capsule,
Bowman’s Capsule characteristics
Double layered cup-shaped dilation of nephron with inner visceral layer and parietal outer layer that are both divided by bowman’s space.
Parietal layer of bowman’s capsule
outer layer of simple squamous epithelium
Visceral layer of bowman’s capsule
inner layer of podocytes in contact with endothelium of glomerular capillaries
Main function of renal corpuscle
producing filtrate of blood
Intraglomerular mesangial cells
Between capillaries in the glomerulus and cover endothelium not covered by podocytes
Extraglomerular mesangial cells
Located between afferent and efferent arterioles at the vascular pole and are associated with the juxtaglomerular apparatus
What are the components of the juxtaglomerular apparatus?
Macula Densa
Extraglomerular mesangial cells
Juxtaglomerular cells
Macula Densa cells are found in walls of _____. They signal ____ from Juxtaglomerular cells and are also involved in regulation of _________ and _____.
convoluted tubule
renin
fluid-electrolyte balance and blood pressure regulation
Five parts of renal tubule are
Proximal convoluted tubule Descending limb of henle loop of henle Ascending limb of henle Distal convoluted tubule...continuous with collecting duct
Proximal convoluted tubule histology
Simple cuboidal epithelium with truncated pyramidal cells
Apical tight junctions and brush border
Abundant mitochondria
Large, pale-staining nuclei
Thick segments of loop of henle are composed of
simple low cuboidal epithelium
No brush border
More basal vertical striations
Thin segments of the loop of henle are compose of
simple squamous epithelium
Distal convoluted tubule histology
simple cuboidal epithelium like the proximal except..smaller
No brush border…unlike proximal convoluted tubule
Impermeable to water…except in presence of ADH (unlike proximal)
The collecting duct has ____ epithelium with cell types: ___ and ___
simple cuboidal
Prinicipal
Intercalated
