RENAL FUNCTION AND RENAL FUNCTION TEST Flashcards

1
Q

it supplies blood to the kidney

A

renal artery

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2
Q

how much blood flow do kidneys receive?

A

25%

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3
Q

based on average body size of

A

1.73m^2

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4
Q

total renal blood flow

A

1200mL/min

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5
Q

total renal plasma flow

A

600 to 700mL/min

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6
Q

functions of kidney

A
  1. Maintaining homeostasis
  2. Excretion of waste products
  3. Concerned with the maintenance
    of blood pressure and
    erythropoiesis
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7
Q

it consists of eight capillary lobes referred to as capillary ducts

A

glomerulus

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8
Q

molecular weight of glomerulus

A

<70,000

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9
Q

where is the glomerulus located?

A

bowman’s capsule

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10
Q

what are the pores in capillary wall membrane called?

A

fenestrated

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11
Q

pores that increase capillary permeability but do not allow the passage of large
molecules and blood cells.

A

fenestrated

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12
Q

restriction of large molecules occurs as the filtrate passes

A

Basement membrane (basal lamina)

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13
Q

the thin membranes covering the filtration slits formed by
the intertwining foot processes of the podocytes of the
inner layer of Bowman’s capsule

A

Visceral epithelium of Bowman’s capsule.

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14
Q

necessary to overcome the opposition of pressure from the fluid from the Bowman’s
capsule and the ONCOTIC PRESSURE of unfiltered plasma protein.

A

HYDROSTATIC PRESSURE

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15
Q

this mechanism maintains the glomerular blood pressure at a relatively constant rate

A

Autoregulatory mechanism

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16
Q

Dilation of the afferent arterioles and constriction of the
efferent arterioles

A

BP drops

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17
Q

it regulates the flow of blood to and within the glomerulus.

A

RAAS (Renin-Angiotensin-Aldosterone System)

18
Q

This system respond to changes in blood pressure and plasma sodium content

A

RAAS (Renin-Angiotensin-Aldosterone System)

19
Q

this monitors the Renin-Angiotensin-Aldosterone System

A

JUXTAGLOMERULAR APPARATUS

20
Q

The body cannot lose 120 mL of water-containing essential substances every
minute

A

TUBULAR REABSORPTION

21
Q

REABSORPTION MECHANISMS

A

ACTIVE TRANSPORT and PASSIVE TRANSPORT

22
Q

Can be influenced by the concentration of the substance being transported.

A

ACTIVE TRANSPORT

23
Q

in active transport, where is substance to be reabsorbed must combined with that is contained in the membranes of the renal tubular cells?

A

carrier protein

24
Q

plasma concentration at which active transport stops.

A

Renal threshold

25
Renal threshold for glucose
160 to 180 mg/dL
26
movement of molecules across membrane as a result of differences in their concentration or electrical potential.
PASSIVE TRANSPORT
27
location of Glucose Amino acids Salts in active transport
Proximal Convoluted Tubule (PCT)
28
location of sodium in active transport
Proximal and Distal Convoluted Tubule (PCT/DCT)
29
location of water in passive transport
Proximal Convoluted Tubule(PCT) Descending Loop of Henle Collecting Duct
30
location of urea in passive transport
Proximal Convoluted Tubule (PCT) Ascending Loop of Henle
31
location of sodium in passive transport
Ascending Loop of Henle
32
where is water removed by osmosis
descending loop of Henle
33
what is reabsorbed in ascending loop of henle?
sodium and chloride
34
a selective reabsorption process that serves to maintain the osmotic gradient of the medulla
countercurrent mechanism
35
where is the final concentration of the filtrate through the reabsorption of water begins
late distal convoluted tubule (and continues in the collecting duct.)
36
2 MAJOR FUNCTIONS OF TUBULAR SECRETION
Elimination of waste products not filtered by the glomerulus Regulation of acid- base balance
37
THIS ACTS AS BUFFER TO THE BLOOD MAINTAINING NORMAL pH
BICARBONATE
38
The standard tests used to measure the filtering capacity of the glomeruli
CLEARANCE TEST
39
how is clearance test reported?
mL/min
40