Renal Drugs Flashcards

1
Q
  • act on DCT and collecting ducts to promote water reabsorption
  • prevents water loss from the body, regulated fluid balance
  • fail safe mechanism
A

Antidiuretic Hormone (ADH)

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2
Q
  • increases reabsorption of Na in DCT and collecting ducts back into the blood
  • this causes an osmotic imbalance which causes water to flow back into the blood along with the sodium
A

Aldosterone

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3
Q

2 drugs contraindicated in patients with uremia.

A

Xylazine and Ketamine

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4
Q

Used to remove excess extracellular fluid by increasing urine flow (diuresis) and Na excretion and reducing hypertension

A

Diuretic Drugs

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5
Q
  • inhibits tubular reabsorption of Na at loop of Henle
  • most rapid with tremendous diuresis
  • side effects: hypokalemia
A

Loop Diuretics

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6
Q
  • duration of action is longer than loop diuretics

- these drugs cross the placental border

A

Thiazide Diuretics

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7
Q
  • weaker diuretic and antihypertensive effects, but they do conserve potassium
  • aka aldosterone antagonist
A

Potassium-Sparing Diuretics

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8
Q
  • reduce intraocular pressure
  • side effect: metabolic acidosis - tachypnea, twitching, mouth ulcers, weight loss, muscle loss
  • block action of carbonic anhydrase which is used by the body to maintian acid-base balance
A

Carbonic Anhydrase Inhibitor

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9
Q

What is the term for the definition given below?

Lack of voluntary control over the normal excretion of urine

A

Urinary incontinence

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10
Q
  • treats retention, helps to void the bladder
  • used in pets with damage to the nerves that control relaxation of the bladder
  • increases tone of detrusor muscle and decreases bladder capacity
  • do NOT use if integrity of the bladder is not known
A

Cholinergic Agents

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11
Q

used to treat urge incontinence by promoting the retention of urine

  • their action produces muscle relaxation
  • side effects: ssssllloooowwwww
A

Anticholinergic Agents

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12
Q
  • reduce internal sphincter tone when the urethral sphincter is in hypertonus
  • treats urinary retention bc of detrusor areflexia or functional urethral obstruction
  • side effects: syncope
A

Alpha Adrenergic Antagonists

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13
Q

-controls mild to moderate hypertension associated with CRF

A

Beta Adrenergic Antagonist

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14
Q

Non-Neurologic Urinary Disorders

A

includes: hormone responsive, stress, urge, ecotopic ureters, over distention

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15
Q

Estrogen treats . . . ?

A

hormone responsive urinary incontinence mainly seen in spayed female dogs

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16
Q

Regulates bp and water balance

A

Renin-Angiotensin-Aldosterone-System

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17
Q

Angiotensin II _______ bld vess which incr bp and secretes ________.

A

Constricts / Aldosterone

18
Q

Aldosterone causes ______ and ______ reabsorption into blood which increases fluid in the body and increases blood pressure.

A

Na / Water

19
Q
  • block angiotensin I to II
  • decreases aldosterone
  • decreases peripheral arterial resistance
  • alleviates vasoconstriction
  • ALL which drop bp
A

Ace Inhibitors

20
Q

True or False: Each type of urolith may be treated differently and and may include dietary management as well as drug treatment.

A

True

21
Q

-used to produce acid urine

A

Urinary Acidifiers

22
Q
  • used in the mgmt of ammonium acid urate, calcium oxalate, and cystine urolithiasis
  • difficult to dissolve calcium oxalate crystals without altering calcium metabolism in body
A

Urinary Alkalizers

23
Q
  • decrease the production of uric acid

- found mostly in dalmatians and patients with gout

A

Xanthine Oxidase Inhibitors

24
Q
  • found covering the transitional epithelium of the urinary tract
  • they keep microorganisms and crystals from adhering to the bladder wall
  • FLUTD
  • cranberry juice
A

Glycosaminoglycans (GAGs)

25
Q

claims to have the potential to reduce azotemia through enteric dialysis

A

Azodyl

26
Q

Renin converts angiotensin I to II by ____?

A

Ace

27
Q

loop diuretics

A

furosemide (lasix)

28
Q

Osmotic Diuretics

A

glucose, mannitol

29
Q

Thiazide Diuretics

A

hydrochlorothiazide

30
Q

Potassium-Sparing Diuretics

A

spironolactone

31
Q

Carbonic Anhydrase Inhibitor

A

acetazolamide

32
Q

Cholinergic Agents (Expulsion)

A

bethanechol

33
Q

Anticholinergic Agents (Retention)

A

propantheline

34
Q

Alpha Adrenergic Antagonists

A

prazosin, phenoxybenzamine

35
Q

Beta Adrenergic Antagonist

A

propanolol

36
Q

Ace Inhibitors

A

benazepril, captopril, enalapril

37
Q

Urinary Acidifiers

A

methigel

38
Q

Urinary Alkalizers

A

potassium citrate, sodium bicarbonate

39
Q

Xanthine Oxidase Inhibitors

A

allopurinol

40
Q

Antidiuretic Hormone (ADH)

A

vasopressin