Renal Diseases Flashcards
Nonimmunologic causes of glomerular damage include exposure to chemicals and toxins that also affect the tubules, disruption of the electrical membrane charges
Nephrotic Syndrome
result from immunologic disorders throughout the body, including the kidney
Glomerular disorders
refers to a sterile, inflammatory process that affects the glomerulus and is associated with the finding of blood
Glomerulonephritis
Glomerulonephritis: (9)
- Acute Poststreptococcal Glomerulonephritis
- Rapidly Progressive (Crescentic) Glomerulonephritis
- Goodpasture Syndrome
- Wegener Granulomatosis
- Henoch-Schönlein Purpura
- Membranous Glomerulonephritis
- Membranoproliferative Glomerulonephritis
- Chronic Glomerulonephritis
- Immunoglobulin A Nephropathy
Nephrotic Syndrome: (2)
- Minimal Change Disease
- Focal Segmental Glomerulosclerosis
Deposition of immune complexes, formed in conjunction with group A Streptococcus infection, on the glomerular membrane.
Acute Post streptococcal Glomerulonephritis
Deposition of immune complexes from systemic immune disorders on the glomerular membrane.
Rapidly progressive glomerulonephritis
Attachment of a cytotoxic antibody formed during viral respiratory infections to glomerular and alveolar basement membranes
Goodpasture syndrome
Antineutrophilic cytoplasmic autoantibody binds to neutrophils in vascular walls producing damage to small vessels in the lungs and glomerulus
Wegener granulomatosis
Occurs primarily in children following viral respiratory infections; a decrease in platelets disrupts vascular integrity
Henoch-Schönlein
purpura
Thickening of the glomerular membrane following IgG immune complex deposition associated with systemic disorders
Membranous glomerulonephritis
Cellular proliferation affecting the capillary walls or the glomerular basement membrane, possibly immune-mediated
Membranoproliferative
glomerulonephritis
Marked decrease in renal function resulting from glomerular damage precipitated by other renal disorders
Chronic glomerulonephritis
Deposition of IgA on the glomerular membrane resulting from increased levels of serum IgA
IgA nephropathy
Disruption of the shield of negativity and damage to the tightly fitting podocyte barrier resulting in massive loss of protein and lipids
Nephrotic syndrome
Disruption of the podocytes occurring primarily in children following allergic reactions and immunizations
Minimal change disease
Disruption of podocytes in certain areas of
glomeruli associated with heroin and analgesic abuse and AIDS
Focal segmental glomerulosclerosis
Genetic disorder showing lamellated and thinning glomerular basement membrane
Alport syndrome
Damage to renal tubular cells caused by ischemia or toxic agents
Acute tubular necrosis
Inherited in association with cystinosis and Hartnup disease or acquired through exposure to toxic agents
Fanconi Syndrome
Inherited defect in the production of normal uromodulin by the renal tubules and increased uric acid causing gout
Uromodulin-associated kidney disease
Inherited defect of tubular response to ADH or acquired from medications
Nephrogenic diabetes
insipidus
Inherited autosomal recessive trait. Benign disorder.
Renal glucosuria
Ascending bacterial infection of the bladder
Cystitis