Renal Disease Flashcards
It result from immunologic disorders throughout the body, including the kidney.
Glomerular Disorder
Immune complexes formed as a resuld of immunologic reaction and increased serum immunoglobulin such as?
Immunoglobulin A(IgA)
Refers to a sterile, inflammatory process that affects the glomerulus & is associated with the finding of blood, protein and casts in the urine.
Glomerulonephritis
A disease marked by sudden onset of symptoms consistent w/ damage to the glomerular membrane, it has infection cused by certain strains of group A beta hemolytic streptococci that contain M protein in the cell wall.
Acute poststreptococcal glomerulonephritis
A more serious form of acute glomerular disease is called?
It has much poorer diagnosis, often terminating in renal failure
Rapidly progressive (crescentic) glumerulonephritis
Rapid progressive glomerulonephritis Often as complication of another form of glomerulonephritis or a disorder of immune system such as?
SLE (Systemic lupus Erythematosus)
Morphological changes to the glomeruli resembling those in rapidly progressive glomerular nephritis are seen in conjunction the autoimmune disorder termed?
Goodpasture syndrome
GPA is formerly known as?
Wegener granulomatosis
It causes a granuloma producing inflammation of the small blood vessels, primarily of the kidney & respiratory system
Granulomatosis with polyangitis
It is the key diagnosis of GPA
Antineutrophilic cytoplasmic antibody
Testing for ANCA that is found in patien’s serum in ehtanol?
Testing for ANCA that is found in patien’s serum in formalin/formaldehyde?
Ethanol- P-ANCA
Formalin/formaldehyde- C-ANCA
Disease that primarily occurs in children after respiratory infections, initial symptoms include the appearance of raised, red patches on the skin.
Henoch-schonlein purpura
Disease associated with membranous glomerulonephritis
SLE
SJOGREN SYNDROME
SECONDARY SYPHILIS
HEPA B
GOLD & MERCURY TREATMENT
MALIGNANCY
A pronounced thickening of the glomerular basenent membrane resulting from the deposition of immunoglobulin G immune complexes
Membranous glomerulonephritis
Is marked by different alterations in the cellularity of the glomerulus and peripheral capillaries
Membranoproliferative glomerulonephritis
Type 1 membranoproliferative glomerulonephritis
Increased cellularity in the subendothelial cells of the interintestinal area of bowman capsule
Type 2 membranoproliferative glomerulonephritis
extreme dense deposits in the glomerular basenent membrane, tubules and bowman capsules
Type 3 membranoproliferative glomerulonephritis
Both subepithelial and subendothelial deposit