Renal Cases and Foley Lab Flashcards
1
Q
75% of renal masses are what?
A
Renal cell carcinoma
2
Q
Where does renal cell carcinoma arise from
A
Kidney parenchyma (as opposed to urothelial cancer which is from renal pelvis/calices)
3
Q
Most common metastatic sites for RCC
A
Most common is lung
Can also be bone or regional LNs
4
Q
5 subtypes of RCC and most common subtype
A
Clear cell (70-80% of cases) Papillary renal cell Chromophobe Medullary Collecting duct
5
Q
Most common hereditary type of RCC
A
Von Hippel-Lindau (VHL) predisposes to clear cell RCC and vascular lesions
6
Q
Risk factors for RCC
A
Prior RCC diagnosis Smoking Obesity HTN Renal failure Acquired renal cystic disease Tuberous sclerosis Heavy meat and high fat dairy products Low SES Heavy metal exposure Other toxin exposure
7
Q
Conditions associated with RCC other than VHL
A
Tuberous sclerosis Hereditary leiomyomatosis Sickle cell trait Adult polycystic kidney disease Renal cystic disease
