renal and acid base physiology

Question 1

which of the folowwing has the highest renal clearance

a) PAH
b) inulin
c) glucose
d) Na
e) Cl

Answer 1

PAH (both filtered and secreted)

Question 2

marker subtance for ECF

Answer 2

mannitol, inulin, sulfate

Question 3

marker substance for TBW

Answer 3

tritiated water, (D2O, antipyrene)

Question 4

marker substance for plasma

Answer 4

evans blue, (RISA)

Question 5

ICF=

Answer 5

TBW-ECF (indirect)

Question 6

oxygen inhibits reabsorption by stopping NA-K pump in the basolateral membranes T/F?

Answer 6

T

Question 7

major actions of PTH on the kidney

Answer 7

1. inhibition of P(phosphate) reabsorption
2. stimulation of Ca
3. stimulation of 1,25dihydroxycholecalsiferol

Question 8

by which segment of the kidney is K secreted

Answer 8

late distal tubule and collecting ducts

Question 9

alkalinization or acidification of the urine leads to increased acid excretion?

Answer 9

alkalinization, —-> acid mostly in the form of A—–> charged —-> cannot backdiffuse —->trapped in urine ——> excreted

Question 10

effects of aldosterone

Answer 10

1. incr Na reabsorption
2. incr K secretion
3. incr H secretion