Renal Anatomy/Physiology Flashcards
four main components of urinary system
kidney
ureters
bladder
urethra
function of the kidneys
produce urine
metabolic balance
produce hormones
what hormones are the kidneys responsible for?
erythropoietin- RBC production
Calcitriol- supply Ca to Bones
Renin- control BP
where are kidneys located
retroperitoneally
T11-L3
what are the internal layers of the kidney?
Cortex Medulla Minor calyces Major calyces renal pelvis
where is cortisol made
cortex of adrenal gland
zona fasciculata
where are sex hormones created
zona reticularis
what is the main functional until of the kidney
nephron
what layers are the nephron found
cortex and medulla
how many nephrons per kidney
1 million
what process for urine formation
blood filtration, reabsorption, secretion in nephron
what makes up a nephron
glomerulus-blood filtration
proximal convoluted tubule- reabsorption
loop of Henle- reabsorption
distal convoluted tubule- reabsorption
where do nephrons drain
collecting ducts
what are the two nephron types
cortical- SHORT loop
juxtamedullary- deep into medulla- LONG loop of Henle
blood passes through the kidney at a rate of
~1200 ml/min or 600 ml/min/kidney
layers of the glomerulus
squamous epithelium (parietal epithelia) basal lamina visceral layer= podocytes=visceral epithelial
three major components of glomerular capillary wall
endothelial cell with fenestra
glomerular basement membrane (GBM)
visceral epithelial cells (podocytes)
ultrafiltrate is made up of
water electrolytes glucose aminoacids urea uric acid creatineine ammonia