Renal Flashcards
Hematuria where’s the blood coming from
Kidney/ureter = blood the whole time Bladder = blood at the end Urethra = blood at the beginning
Urethral stricture
Obstructive sx slow urine stream, dribbling, spraying, large postvoid residual, NO UTI SX, cause often unknown
Membranous nephropathy
Hep B
Why do we treat pregnant women w asx bacteriuria
Prevent pyelo (ureteral smooth muscle relaxes higher risk asc infx), ARDs preterm labor
Stones
Don’t see on XR: (SUCCX)
- Struvite (urease-prod bact)
- Uric acid (tx K citrate alk urine)
- Ca 1-3mm (envelope crystals)
- Cysteine (SIXteen=hexagonal crystals, genetic, COLA, cyanide nitroprusside test)
- Xanthine
Radiopaque:
- Ca oxalate >3mm
AKI
Def=<600mL/24h, Cr inc >50%
Prerenal BUN/Cr>20, UNa<20 appropriately low (kidneys are working), nl UA:
- hypovolemia (sepsis, DIURETICS)
- maybe CHF
Intrarenal BUN/Cr 10-15, UNa>40:
- acyclovir crystals direct damage to tubules 24-48h
- AIN rx (blactams other abx, PPI >7 days after start the rx) OR systemic dz, WBC casts
- ATN ischemic injury, can be 2/2 hypovolemia, Uosm >300, UNa >20, FeNa >2% (kidneys suck), give fluids MUDDY BROWN CASTS
- Glomerulonephritis RBC CASTS (+/- few WBC)
Postrenal hydronephrosis:
- BPH
- cancer
Blunt abd trauma, pelvic injury PERITONITIS
Bladder dome rupture (ant wall and neck of bladder are extraperitoneal)
W/u for recurrent UTIs in kids
US: <2 yo 2+ UTIs Family hx renal dz Abx don’t work
Voiding cystourethrogram:
Newborn <1 mo
2+ UTIs
Not E. coli
Diabetic glomerulosclerosis course
1 Glomerular hyperfiltration —> intraglom hypertension ACEi reduce htn
2 BM thickening
3 mesangial expansion
4 nodular sclerosis
DM nephropathy Screening check microalbumin (dipstick detects protein >300, in DM have protein 30-300)
Nocturnal enuresis
> 5 yo, lifestyle, alarm, desmopressin
Indications to remove a stone
Time >1mo
Size >1cm
Stuck (complete obstruction)
Sick (AKI, sepsis, PAIN)
Sickle cell TRAIT kidney stuff
Hypostenuria (kidney can’t concentrate the urine)
Renal papillary necrosis (hematuria)
Rhabdo
SSRI
SIADH!
Posterior urethral injury
Pelvic fx, blood in urethral meatus, perineal hematoma, inability to urinate, high-riding prostate, dx retrograde urethrography
Proteinuria in a preggo
Physiologic = trace, dec Cr, hypotens
Diabetic nephropathy = >300 or 1+ protein, inc Cr, hypertension, if <20w likely preexisting
Polycystic kidney disease
AD
B/l masses, berry aneurysms, hepatic cysts, INTERMITTENT recurrent b/l flank pain (w/ gardening) +/- hematuria, early onset HTN
HYPERKALEMIA!! Treatment
IF >7 or EKG changes —> Give calcium gluconate or chloride NOT CARBONATE, insulin + glucose, inhaledB2 agonists
Drug to help pass a kidney stone
Tamsulosin a1 antagonist
Bethanechol cholinergic tx for retention
Oxybutinin antichol tx for OAB
Drugs that cause hyperK
Notoriously Bad Potassium
NSAIDs
BP drugs (ACEi, ARB, amiloride, Bb, spironolactone)
Symptomatic hyponatremia (encephalopathy)
6-8 per 24h, if iatrogenic from hypotonic fluids can give hypertonic
Interstitial cystitis
Clean UA, pain, tx supportive
Mixed acid-base disorders compensatory
Metabolic acidosis, CO2 should be lower to compensate—> CO2=1.5(HCO3) + 8 +-2
Metabolic alkalosis—> CO2 INC 0.7/1 HCO3 >28
Respiratory acidosis—> bicarb INC 1/10 acute, 4/10 chronic
Respiratory alkalosis—> bicarb DEC 2/10 acute, 5/10 chronic