Renal

Question 1

GFR

Answer 1

GFR = KF x (PGC - PBS - πGC) | KF is the filtration coefficient, the product of the permeability of the filtration barrier and the surface area available for filtration

Question 2

Filtration Fraction (FF)

Answer 2

GFR / Renal Plasma Flow | i.e. the filtration fraction is the fraction of the renal blood that gets filtered - renal blood flow = 1000ml/min but only 60% of blood is plasma (40% being cellular components) so 600ml/min is the renal plasma flow

Question 3

Urine Output

Answer 3

0.5ml/kg/hr

Question 4

Renal Clearance

Answer 4

Clearance = (Urine Concentration x Urine Volume) / Plasma Concentration

Question 5

Anion Gap

Answer 5

Anion Gap = ([Na+] + [K+]) + ([Cl-]+[HCO3-]) | normal = approx. 16, large gap suggests metabolic acidosis