Renal Flashcards
Parasympathetic innervation of kidney
Kidney DOES NOT HAVE PARASYMPATHETIC INNERVATION
Filtration fraction
RPF (renal plasma flow)
What increases filtration fraction?
Vasoconstriction of afferent and efferent
FILTRATION FRACTION and ONCOTIC PLASMA PRESSURE
If FF increase: Oncotic pressure increases in peritubular capillary: no filtration
Filter load
FL= GFR x Px
Filter load)= (Glomerular filtration rate) x (concentration of substance in plasma
Excretion rate
ER= Ux x V
Excretion rate = Urine concentration of substance x Urine flow rate
Net transport rate
NTR= FL - ER
Clearance
Clearance= ER (Ux x V(Flow))
—-
Px
excretion rate -------------- plasma concentration
Clearance of glucose
0
Clearance of albumin
0
Clearance of inulin
Equal to GFR
Clearance of PAH
Equal to RPF
Maximum transporte of glucose TM
375 mg/min
Substance no secreted no reabsorbed
Insulin
Substance secreted
PAH and creatinine
Renal blood flow
RBF= RPF
—- x HCT
1
RBF= renal plasma flow x Hematocrit
——————
1
Highest to lowest clearance of substances:
PAH > creatinine > insulin > urea > Na> glucose = albumin
Free water clearance
CH2O= V - Uosm x V
—————
P Osm
CH2O +
Hypotonic urine
CH2O -
Hypertonic urine
What aldosterone does with FeNa?
Decreases FeNa
It stimulates reabsorption, so reduces excretion
What does ANP with FeNa?
Increases FeNa
It stimulates excretion