Renal

Question 1

If hypopituitarism is caused by craniopharyngioma, where would it be located in relation to the sella turcica? What would be seen there?

Answer 1

• Tumor forms above the sella turcica
• Supracellar calcification

Question 2

Aside from small cell carcinoma of the lung, what other cancers are associated with SIADH? (6)

Answer 2

• Prostate, GI, and pancreatic carcinomas; thymoma, lymphoma, and Hodgkins lymphoma

Question 3

Pituitary adenomas is an enlargement of anterior or posterior lobe? How does this affect the endocrine fxns of the pituitary?

Answer 3

• Anterior
• Causes increased secretion of whichever ant pituitary hormone cell is affected (endocrine hyperfxn)

Question 4

What is the most common type of pituitary adenoma?

Answer 4

Prolactinoma

Question 5

Thymoma and thymic hyperplasia are associated with what autoimmune disorder?

Answer 5

Myasthenia Gravis

Question 6

What is the most common cause of hypoparathyroidism?

Answer 6

Surgical resection as a complication of thyroidectomy is the most common cause

Question 7

Give an example of a genetic cause of hypoparathyroidism.

Answer 7

DiGeorge Syndrome

Question 8

What inheritance pattern does Congenital Adrenal Hyperplasia follow?

Answer 8

Autosomal Recessive

Question 9

What changes to the thymus can be expected in Wiskott-Aldrich Syndrome?

Answer 9

Thymus hypoplasia

Question 10

Hypocalcemia seen in Albright hereditary osteodystrophy is caused by what?

Answer 10

Albright hereditary osteodystrophy is a type of pseudohypoparathyroidism, where PTH is present but does not have its effect due to end-organ-insensitivity –> Ca2+ wasting by renal tubules –> hypocalcemia