renal Flashcards
1
Q
which drugs stimulate ADH production?
A
morphine
barbiturates
nicotine
Amphetamines
2
Q
where is ADH made?
A
cell bodies of supraoptic and paraventricular nucleus of hypothalamus
3
Q
what type of molecule is ADH?
A
9 aa oligopeptide
4
Q
what is normal GFR?
A
125ml/min
180L/day
5
Q
what is the osmolarity of the renal papillae?
A
1200mOsm/L - 1400
6
Q
what is renal blood flow?
A
20% of CO
around 1L/min
7
Q
what is a normal value of specific gravity of urine?
A
1.01 to 1.03
can also be written as 1010 to 1030
unlikely to be less than 1010 unless drank loads of water
8
Q
how does Angiotensin II affect GFR?
A
Angiotensin II causes mesangial cells to contract, which decreases the filtration coefficient
9
Q
why is albumin not filtered at the glomerulus ?
A
MW 67KDa
negative charge
10
Q
A
