Renal

Question 1

AKI

What are the three groups of causes of an AKI?

Answer 1

Pre-renal
Renal
Post-renal

Question 2

AKI

What is the definition of a pre-renal cause of an AKI?

Answer 2

Reversible impairment of renal function from relative hypovolaemia or hypoperfusion

Question 3

AKI

What is the definition of a renal cause of an AKI?

Answer 3

Damage within a kidney which could result from more severe ischaemia, sepsis, inflammation, or toxicity

Question 4

AKI

What is the definition of a post-renal cause of an AKI?

Answer 4

Obstruction of urine outflow causing a damaging “back pressure” within the kidney

Question 5

AKI

What is classed as Stage 1 AKI?

Answer 5

Creatinine rise of 26 micromol/l or more within 48hrs or
Creatinine rise >/= 1.5 x baseline in 7 days or
Urine output less than0.5 ml/kg/hr for >6 hours

Question 6

AKI

What is classed as Stage 2 AKI?

Answer 6

Creatinine rise >/= 2 x baseline or
Urine output less than 0.5 ml/kg/hr for >/= 12 hours

Question 7

AKI

What is classed as Stage 3 AKI?

Answer 7

Creatinine rise to 354 micromol/l or more with either
* Acute rise in creatinine of >/= 26 micromol/l within 48 hours or
* >/= 50% rise from baseline within 7 days or
Creatinine rise >/= 3 x baseline in 7 days or
Urine output less than 0.3 ml/kg/hr for >6 hours or
Anuria for 12 hours or
Any requirement for renal replacement therapy