Renal Flashcards
Initiating event (Kidney injury)
Symptoms of the underlying illness causing AKI may be present
Oliguric or anuric phase (Maintenance phase)
Progressive deterioration of kidney function
-Reduced urine production (oliguria), <50 ml/24 hrs=anuria
-Increased retention of urea and creatinine (azotemia)
Complications: fluid retention (pulmonary edema), hyperkalemia, metabolic acidosis, uremia, lethargy, asterixis
Polyuric/diuretic phase
-Glomerular filtration returns to normal, which increaces urine production (polyuria), while tubular reabsorption remains disturbed
-Complications: Loss of electrolytes and water (dehydration, hyponatremia and hypokalemia)
Recovery Phase
Kidney function and urine production normalize
AKI Stage 1
Serum Creatinine: Increase of 0.3 mg/dL(26.5 umol/L) OR 1.5-1.9 times baseline
Urine Output: <0.5mL/kg/hour for 6-12 hours
AKI Stage 2
Serum Creatinine: 2.0-2.9 times baseline
Urine output: <0.5 mL/kg/hour for >12 hours
AKI stage 3
Serum Creatinine: >3 times baseline, OR increase >4mg/dL (354 umol/L)
OR Renal replacement therapy initiated
OR in pateints < 18 years of age decrease in eGFR to <35 mL/min/1.73 m2
Urine output: 0.3 mL/kg/hour for 24 hours OR anuria for >12 hours
CKD obstructive nephropathy
Ureteral or Renal pelvic dilation
CKD :PCKD
Bilaterally enlarged kidneys with multiple cysts
CKD: Chronic glomerulonephritis/Pyelnophritis
Cortical nephrocalcinosis
Hyrdonephrosis Grade 1
Renal pelvic dilation
Hydronephrosis Grade 2
Pelvis+ Caliceal dilation
Renal parenchyme (Medulla and Cortex) are normal (>7mm)
Hydronephrosis Grade 3
Pelvis and Caliceal Dilation
Medulla is short and thin
Cortex is normal